Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Hepatoblastoma	NCIT_C3728	[A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.]
Second-Look Surgery	NCIT_C15317	[Surgery performed after cancer treatment to assess the results of prior treatment and to plan possible future treatment.]
Reproducibility	NCIT_C15318	[The ability to yield similar results given a set of constraints.]
Research	NCIT_C15319	[Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered.]
Extraskeletal Ewing Sarcoma	NCIT_C7135	[A rare malignant neoplasm of the soft tissues. It is typically a disease of children and young adults. Most commonly occurs in the paravertebral region, chest wall, pelvis and lower extremities. Treatment includes local excision with consideration for post-operative chemotherapy and/or radiotherapy.]
Malignant Soft Tissue Tumor of Uncertain Differentiation	NCIT_C6588	[A malignant soft tissue tumor in which the line of differentiation is uncertain.]
Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor	NCIT_C27293	[A spectrum of malignant tumors arising from the soft tissues, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.]
Ewing Sarcoma	NCIT_C4817	[A small round cell tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It affects mostly males under age 20, and it can occur in soft tissue or bone. Pain and the presence of a mass are the most common clinical symptoms.]
Extracutaneous Mastocytoma	NCIT_C7136	[A localized tumor consisting of mature mast cells. (WHO, 2001) -- 2003]
Mastocytoma	NCIT_C9303	[A localized tumor composed of sheets of mast cells without atypia. It includes the cutaneous mastocytoma which involves the dermis and subcutaneous tissue, and the extracutaneous mastocytoma. Most cases of extracutaneous mastocytoma have been reported in the lung.]
Cutaneous Mastocytosis	NCIT_C7137	[A form of mastocytosis characterized by mast cell infiltration of the skin. (WHO, 2001)]
Dermal Neoplasm	NCIT_C4475	[A benign, intermediate, or malignant neoplasm that arises from the dermis.]
Mastocytosis	NCIT_C84269	[A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ systems. It is a heterogeneous group of neoplasms, ranging from cutaneous proliferations which may regress spontaneously, to aggressive neoplasms associated with organ failure and short survival.]
Solitary Mastocytoma of the Skin	NCIT_C7138
Pure Cutaneous Mastocytosis	NCIT_C43277
SNRPF Gene	NCIT_C29960	[This gene plays a role in nuclear mRNA splicing.]
snRNP Biogenesis	NCIT_C30092	[The 4 major small nuclear ribonucleoprotein particles (snRNPs), U1, U2, U4/U6, and U5, share 8 proteins which form the snRNP structural core: SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, and SNRPG. These common proteins play an essential role in the biogenesis of the snRNPs. The assembly of the common proteins onto the small nuclear RNA (snRNA) appears to occur in at least 2 steps and involves the formation of RNA-free protein heterooligomers. (from OMIM)]
SHC-Transforming Protein 3	NCIT_C29961	[SHC-transforming protein 3 (594 aa, ~64 kDa) is encoded by the human SHC3 gene. This protein is involved in the mediation of growth factor receptor-dependent signaling pathways in neurons.]
Sonic Hedgehog Protein	NCIT_C29962	[Sonic hedgehog protein (462 aa, ~50 kDa) is encoded by the human SHH gene. This protein plays a role in embryonic pattern formation.]
12q23.1	NCIT_C29963	[A chromosome band present on 12q]