Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
ADCS-ADL MCI - Use Household Appliance: Microwave	NCIT_C106937	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, check household appliances that apply: microwave.]
ADCS-ADL MCI - Use Household Appliance: Food Processor	NCIT_C106938	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, check household appliances that apply: food processor.]
ADCS-ADL MCI - Use Household Appliance: Other	NCIT_C106939	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, check household appliances that apply: other.]
Thyroid Cancer pM1 TNM Finding v6 and v7	NCIT_C60798	[Thyroid cancer with distant metastasis. (from AJCC 6th and 7th Eds.)]
Thyroid Cancer Pathologic Distant Metastasis TNM Finding v7	NCIT_C89156	[A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. There is no pathologic M0 for thyroid cancer.]
Thyroid Cancer pMX TNM Finding v6	NCIT_C60799	[Thyroid cancer in which the status of distant metastasis cannot be assessed. (from AJCC 6th Ed.)]
Pasireotide	NCIT_C69131	[A synthetic long-acting cyclic peptide with somatostatin-like activity. Pasireotide activates a broad spectrum of somatostatin receptors, exhibiting a much higher binding affinity for somatostatin receptors 1, 3, and 5 than octreotide in vitro, as well as a comparable binding affinity for somatostatin receptor 2. This agent is more potent than somatostatin in inhibiting the release of human growth hormone (HGH), glucagon, and insulin.]
Somatostatin Receptor Agonist	NCIT_C62799	[Any of the synthetic agents that bind to somatostatin receptors and mimic the actions of somatostatin.]
NCI Criterion	NCIT_C69132	[Criteria established for assigning high-frequency microsatellite instability (MSI-H) in cancers requiring that at least two of five markers (BAT25, BAT26, D2S123, D5S346, D17S250) score positive for MSI.]
Diagnostic or Prognostic Factor	NCIT_C20047	[A characteristic of an organism that contributes to the diagnosis or treatment of a disease or to the prediction of clinical outcomes.]
Collagen/Aloe Vera/Vitamin E/Lidocaine Topical Hydrogel	NCIT_C69133	[A topical preparation containing collagen, aloe vera, vitamin E, and lidocaine hydrochloride with wound-healing activity. The four ingredients of collagen/aloe vera/vitamin E/lidocaine topical hydrogel may promote wound repair and new tissue growth in which: collagen, a structural protein in connective tissue, provides a connective tissue matrix for the attachment of various cells involved in wound repair; aloe vera carbohydrate polymers provide a moist wound environment; vitamin E promotes blood vessel formation; and lidocaine acts as a local anesthetic.]
Topical Preparation	NCIT_C29639	[Natural or synthetic compounds or mixtures that are applied to body surfaces such as the skin, mouth, vagina, lips, nose, ears or the eyes. A topical preparation can act only on the specific area to which it is applied or it can be applied locally to be absorbed into the blood stream and act systemically.]
Apoptosis Inducer BZL101	NCIT_C69134	[An orally active aqueous extract derived from the plant Scutellaria barbata with potential antineoplastic activity. Sparing normal cells, apoptosis inducer BZL101 specifically facilitates translocation of the protein apoptosis-inducing factor (AIF) from the mitochondrial membrane into the nucleus in tumor cells, thereby causing tumor cell-specific chromatin condensation and DNA degradation followed by the induction of caspase-independent apoptosis. AIF is both a mitochondrial intermembrane flavoprotein with oxidoreductase activity and a caspase-independent death effector that, similar to cytochrome c, is released from mitochondria early in the apoptotic process.]
Apoptotic Pathway-targeting Antineoplastic Agent	NCIT_C129839	[Any agent that directly targets the apoptotic pathway and has an antineoplastic effect.]
RAF Kinase Inhibitor XL281	NCIT_C69135	[An orally active, small molecule with potential antineoplastic activity. XL281 specifically inhibits RAF kinases, located downstream from RAS in the RAS/RAF/MEK/ERK kinase signaling pathway, which may result in reduced proliferation of tumor cells. RAS mutations may result in constitutive activation of the RAS/RAF/MEK/ERK kinase signaling pathway, and have been found to occur frequently in human tumors.]
Raf Kinase Inhibitor	NCIT_C2336	[Any substance that inhibits Raf Kinase, an enzyme active in signal transduction in the Ras pathway. Inhibition of Raf kinase may result in reduced cell proliferation and cell death.]
Iodine I-123 Iodometomidate	NCIT_C69137	[An iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a potent and selective inhibitor of the cytochrome P-450 enzymes, especially CYP11B1 (11 beta-hydroxylase) and CYP11B2 (aldosterone synthase). Because both CYP11B1 and CYP11B2 are expressed exclusively in the adrenal cortex, I-123 iodometomidate can be used as a radiotracer for adrenal scintigraphy.]
Radioconjugate	NCIT_C2124	[Compounds comprised of a radioactive agent linked to a pharmacological substance to be used to prevent, diagnose, or treat various diseases, including cancer. (NCI)]
Adult Classic Hodgkin Lymphoma	NCIT_C69138	[Classic Hodgkin lymphoma that occurs in adults.]
Adult Hodgkin Lymphoma	NCIT_C7702	[Hodgkin lymphoma occurring in adults.]