Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Performed Clinical Interpretation Toxicity Grade Code	NCIT_C93906	[A coded value specifying the numeric grade for the toxicity.]
Toxicity Grade Code	NCIT_C93695	[A coded value specifying the numeric grade for the toxicity.]
Collagen Alpha-1(VII) Chain	NCIT_C107115	[Collagen alpha-1(VII) chain (2944 aa, ~295 kDa) is encoded by the human COL7A1 gene. This protein is involved in interactions between squamous epithelia and the basement membrane.]
Collagen	NCIT_C16447	[A family of large fibrous proteins that are the main components of connective tissue and are responsible for maintaining tissue structure.]
Propranolol Hydrochloride	NCIT_C29382	[The hydrochloride form of propranolol, a synthetic beta-adrenergic receptor blocker with antianginal, antiarrhythmic, and antihypertensive properties. Propranolol competitively antagonizes beta-adrenergic receptors, thereby inhibiting beta-adrenergic reactions, such as vasodilation, and negative chronotropic and inotropic effects.]
Performed Clinical Interpretation Toxicity Term Code	NCIT_C93907	[A coded value specifying the degree to which a substance is able to damage an exposed organism.]
Toxicity Term Code	NCIT_C93696	[A coded value specifying the degree to which a substance is poisonous.]
GABARAPL2 Gene	NCIT_C107116	[This gene plays a role in intra-Golgi trafficking.]
Propantheline Bromide	NCIT_C29383	[The bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. An aspartic acid residue present in the N-terminal portion of the third trans-membrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax bronchial muscle and reduce tone and motility of intestinal smooth muscle.]
Performed Clinical Result As Collected Indicator	NCIT_C93908	[Specifies whether the observation is represented in the units or values as originally collected.]
As Collected Indicator	NCIT_C93509	[Specifies whether the entity is represented as originally collected.]
GABARAPL2 wt Allele	NCIT_C107117	[Human GABARAPL2 wild-type allele is located in the vicinity of 16q22.1 and is approximately 12 kb in length. This allele, which encodes gamma-aminobutyric acid receptor-associated protein-like 2, is involved in the regulation of intra-Golgi transport.]
Propofol	NCIT_C29384	[A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.]
Performed Clinical Result Biomarker Indicator	NCIT_C93909	[Specifies whether a result is considered a biomarker.]
Biomarker Indicator	NCIT_C93515	[Specifies whether an entity is considered a biomarker.]
Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 2	NCIT_C107118	[Gamma-aminobutyric acid receptor-associated protein-like 2 (117 aa, ~14 kDa) is encoded by the human GABARAPL2 gene. This protein plays a role in the regulation of intra-Golgi transport.]
Laryngeal Lymphoepithelial Carcinoma	NCIT_C54341	[A rare and aggressive carcinoma that arises from the larynx. It is characterized by the presence of an undifferentiated carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate.]
Laryngeal Undifferentiated Carcinoma	NCIT_C54339	[An undifferentiated carcinoma that arises from the larynx. This category includes lymphoepithelial carcinoma and giant cell carcinoma.]
Propoxyphene Hydrochloride	NCIT_C29385	[The hydrochloride salt form of the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent mimics the effects of the endogenous opiate dextropropoxyphene, by binding to mu receptors located throughout the central nervous system. The binding results in GTP to GDP exchanges on the mu-G-protein complex, by which effector adenylate cyclase is inactivated thereby decreasing intracellular cAMP. This, in turn, inhibits the release of various nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, noradrenaline, vasopressin, and somatostatin. In addition, dextropropoxyphene closes N-type voltage-gated calcium channels and opens calcium-dependent inwardly rectifying potassium channels. This results in hyperpolarization, thereby reducing neuronal excitability, which further decreases the perception of pain.]
Laryngeal Giant Cell Carcinoma	NCIT_C54342	[A rare undifferentiated carcinoma that arises from the larynx. It is characterized by the presence of multiple bizarre multinucleated giant cells. The prognosis is poor.]