Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Grade 5 Suicide Attempt, CTCAE	NCIT_C146571	[Death]
Grade 5 Superficial Soft Tissue Fibrosis, CTCAE	NCIT_C146572	[Death]
Grade 5 Superior Vena Cava Syndrome, CTCAE	NCIT_C146573	[Death]
Grade 5 Surgical and Medical Procedures - Other, Specify, CTCAE	NCIT_C146574	[Death]
Grade 5 Testicular Hemorrhage, CTCAE	NCIT_C146575
Grade 5 Thromboembolic Event, CTCAE	NCIT_C146576	[Death]
Grade 5 Thrombotic Thrombocytopenic Purpura, CTCAE	NCIT_C146577	[Death]
Grade 5 Tooth Infection, CTCAE	NCIT_C146578	[Death]
Tioconazole	NCIT_C29500	[A synthetic imidazole derivative, fungicidal Terconazole inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Tioconazole is active against pathogenic Candida. (NCI04)]
Timolol Maleate	NCIT_C29501	[The maleate salt form of timolol, a propanolamine derivative and a non-selective beta-adrenergic antagonist with antihypertensive property. Timolol competitively binds to beta-1-adrenergic receptors in the heart and vascular smooth muscle and beta-2-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in beta-adrenergic stimulation. Beta-1-receptor blockade results in a decrease in resting and exercise heart rate and cardiac output, a decrease in both systolic and diastolic blood pressure, and, possibly, a reduction in reflex orthostatic hypotension. Beta-2-blockade results in an increase in peripheral vascular resistance. The ultimate results include vasodilation, and negative chronotropic and inotropic effects. In addition, timolol reduces intra-ocular pressure possibly by decreasing aqueous humor production by reduction of blood flow to the ciliary processes and cAMP synthesis.]
Tolazamide	NCIT_C29502	[An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are excreted into the urine. Tolazamide is more potent than tolbutamide and similar in potency to chlorpropamide on a milligram basis. This agent may cause cholestatic jaundice.]
Tolmetin	NCIT_C29503	[An arylalkanoic acid and non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic activities. Although the exact mechanism through which tolmetin exerts its effects has yet to be fully elucidated, this agent appears to inhibit the enzyme prostaglandin synthase. This prevents the formation of prostaglandins from prostaglandin precursors, including the synthesis of the inflammatory prostaglandin E2 (PGE2) from the precursor prostaglandin H2 (PGH2). This prevents prostaglandin-mediated effects, including pain, inflammation and fever.]
Tolterodine Tartrate	NCIT_C29504	[The tartrate salt form of tolterodine, a benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.]
Topical Corticosteroid	NCIT_C29505	[Any synthetic steroid derivative exhibiting the same function as the naturally occurring corticosteroid hormone, formulated for topical application. Topical corticosteroids are applied to the skin where it exerts its effect, however, corticosteroids can be absorbed systemically after being applied locally. Topical corticosteroids are mainly used for the localized treatment of inflammation of the skin and help relieve symptoms such as itching, swelling and redness.]
Grade 5 Stridor, CTCAE	NCIT_C146568	[Death]
Grade 5 Stroke, CTCAE	NCIT_C146569	[Death]
Grade 5 Spasticity, CTCAE	NCIT_C146560	[Death]
Grade 5 Spermatic Cord Anastomotic Leak, CTCAE	NCIT_C146561	[Death]
Grade 5 Spinal Cord Compression, CTCAE	NCIT_C146562	[Death]
Grade 5 Spinal Fracture, CTCAE	NCIT_C146563	[Death]