Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Adult Mesoblastic Nephroma	NCIT_C7648
Anterior Urethral Malignant Neoplasm	NCIT_C7641	[A primary or metastatic malignant neoplasm involving the anterior portion of the urethra.]
Epipodophyllotoxin-Related Myelodysplastic Syndrome	NCIT_C7642	[A disorder seen following cancer chemotherapy. It typically manifests a few years after initiation of epipodophyllotoxin chemotherapy. Mutagenic potential of these non-intercalating DNA topoisomerase II inhibitors is believed to be increased with concurrent use of asparaginase or granulocyte colony-stimulating factor. Balanced translocations involving chromosomal bands 11q23 and 21q22 are commonly associated with this disorder. Clinical signs may include fatigue, dyspnea, bruising and frequent infections. Clinical course usually progresses to acute myeloid leukemia though most epipodophyllotoxin-related leukemias do not have an antecedent myelodysplastic phase. Prognosis is dismal with survivability usually less than one year.]
Therapy-Related Myelodysplastic Syndrome	NCIT_C27722	[A myelodysplastic syndrome caused by chemotherapy and/or radiotherapy.]
Alkylating Agent-Related Myelodysplastic Syndrome	NCIT_C7643	[A disorder seen following cancer chemotherapy. It is the most common cause of therapy-related myelodysplastic syndromes. It typically manifests several years after initiation of single or multi-agent chemotherapy with alkylators. Mutagenic potential of alkylating agents is believed to be age and cumulative dose-dependent. Deletions in chromosomes 5 and 7 are associated with susceptibility to this disorder. Clinical signs may include fatigue, dyspnea, bruising and frequent infections. Clinical course may progress to bone marrow failure or acute myeloid leukemia that is refractory to treatment. Prognosis is dismal with survivability usually less than one year.]
Alkylating Agent-Related Acute Myeloid Leukemia and Myelodysplastic Syndrome	NCIT_C27913	[Acute myeloid leukemias and myelodysplastic syndromes arising as a result of the mutagenic effect of alkylating agents that are used for the treatment of malignant tumors. Patients usually develop a myelodysplastic syndrome which may evolve to a higher grade myelodysplastic syndrome or acute myeloid leukemia. A minority of patients present with an acute myeloid leukemia. Clonal cytogenetic abnormalities are frequently present and usually are unbalanced translocations or deletions of chromosomes 5 and 7. Patients with acute myeloid leukemia usually do not respond to treatment and have an unfavorable clinical outcome.]
Adamantinoma	NCIT_C7644	[A low grade malignant neoplasm arising from the long bones. The tibia is the most frequently affected bone site. Patients present with swelling which may or may not be associated with pain. Morphologically, it is characterized by a biphasic pattern consisting of an epithelial and an osteofibrous component. The vast majority of cases recur if they are not treated with radical surgery. In a minority of cases the tumor may metastasize to other anatomic sites including lymph nodes, lungs, liver, brain, and skeleton.]
Localized Gallbladder Carcinoma	NCIT_C7649	[A carcinoma that arises from the gallbladder and it has not spread to other anatomic sites.]
Posterior Urethral Malignant Neoplasm	NCIT_C7640	[A malignant neoplasm that affects the portion of the urethra that is close to the bladder.]
Liver Dysplastic Nodule	NCIT_C7656	[A premalignant neoplastic nodular lesion of the liver that usually measures less than 15 mm. It is found during microscopic examination of liver tissues, usually in cirrhotic livers. Based on the degree of atypia, it is classified as low or high grade.]
Intestinal Precancerous Condition	NCIT_C7657
Intestinal Disorder	NCIT_C26801	[A non-neoplastic or neoplastic disorder that affects the small or large intestine.]
Intestinal Intraepithelial Neoplasia	NCIT_C7658	[A precancerous neoplastic process that affects the small or large intestine. It is characterized by low or high grade dysplasia of the mucosal epithelium. There is no evidence of invasion.]
Glandular Cell Intraepithelial Neoplasia	NCIT_C27269
Digestive System Intraepithelial Neoplasia	NCIT_C8962	[A non-invasive neoplastic process that affects the epithelium of any part of the digestive system. It is characterized by the presence of morphologic features of dysplasia (e.g., architectural and cytological epithelial alterations) or, in a minority of cases, lack of such morphologic features, as in colonic sessile serrated adenomas/polyps.]
Intestinal Neoplasm	NCIT_C3141	[A benign or malignant neoplasm involving the small or large intestine.]
Cellular Precursor of Cancer	NCIT_C7654
Hepatobiliary Disorder	NCIT_C3959	[A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma.]
Hepatobiliary System	NCIT_C43612	[The liver, gallbladder, and associated ducts, considered collectively.]
Metastatic Malignant Neoplasm in the Bladder	NCIT_C7650	[The spread of a malignant neoplasm to the urinary bladder wall from an adjacent or distant anatomic site.]