Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
BCAS3 wt Allele	NCIT_C54546	[Human BCAS3 wild-type allele is located in the vicinity of 17q23 and is approximately 715 kb in length. This allele, which encodes breast carcinoma amplified sequence 3 protein, may play a role in the cellular response to estrogen. The occurrence of some breast cancers is linked to either aberrant expression of the gene or a chromosomal translocation t(17;20)(q23;q13), which causes the fusion of this gene and the BCAS4 gene.]
BCAS3 Gene	NCIT_C20773	[This gene plays a role in transcriptional regulation.]
BCAS4 wt Allele	NCIT_C54547	[Human BCAS4 wild-type allele is located in the vicinity of 20q13.13 and is approximately 82 kb in length. This allele, which encodes breast carcinoma amplified sequence 4 protein, may be involved in both the progression of breast cancer and the regulation of vesicular trafficking. Some breast carcinomas are linked to either aberrant expression of the gene or a chromosomal translocation t(17;20)(q23;q13), which involves both this gene and the BCAS3 gene.]
BCAS4 Gene	NCIT_C20774	[This gene plays a role in transcriptional regulation.]
Type of Event ICSR Terminology	NCIT_C54580	[Terminology used in Individual Case Safety Reports for identifying the type of event (adverse event or product problem), section B1 of FDA MedWatch Form.]
Intestinal Hemorrhage	NCIT_C54581	[Bleeding originating in the gastrointestinal tract.]
Lower Gastrointestinal Hemorrhage	NCIT_C78438	[Bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus).]
Gastric Hemorrhage	NCIT_C54582	[Bleeding from the gastric wall.]
Upper Gastrointestinal Hemorrhage	NCIT_C78660	[Bleeding originating from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach).]
Adverse Event Outcome ICSR Terminology	NCIT_C54583	[Terminology used in Individual Case Safety Reports for description of adverse event outcomes, section B2 of FDA MedWatch Form.]
Operator of Medical Device ICSR Terminology	NCIT_C54584	[Terminology used in Individual Case Safety Reports to specify information on an operator of a medical device, section D5 of FDA MedWatch Form.]
Occupation ICSR Terminology	NCIT_C54585	[Terminology used in Individual Case Safety Reports to specify information on an occupation of reporter, section E3 of FDA MedWatch Form.]
Seed	NCIT_C54575	[To inoculate with microorganisms.]
Timeline	NCIT_C54576	[A chronological schedule of when activities or events occurred or will occur.]
FDA Device Component Code Hierarchy	NCIT_C54577	[Terminology used for device components or accessories in safety reports and FDA CDRH documents during both pre and post approval periods of device development and usage.]
SOD1 Gene	NCIT_C54578	[This gene plays a role in the detoxification of superoxide radicals in the cytosol.]
Amyotrophic Lateral Sclerosis	NCIT_C34373	[A neurodegenerative disorder characterized by progressive degeneration of the motor neurons of the central nervous system. It results in weakness and atrophy of the muscles which leads to an inability to initiate and control voluntary movements.]
Oxidative Stress	NCIT_C17741	[A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.]
SOD1 wt Allele	NCIT_C54579	[Human SOD1 wild-type allele is located within 21q22 and is approximately 9 kb in length. This allele, which encodes superoxide dismutase [Cu-Zn] protein, is involved in the conversion of superoxide radicals to molecular oxygen and hydrogen peroxide. Certain allelic variants of the SOD1 gene cause Amyotrophic Lateral Sclerosis.]
14q23.1	NCIT_C54570	[A chromosome band present on 14q]