Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Ringing or Other Noises Did Not Wake Me From Sleep	NCIT_C132001	[A response indicating that ringing or other noises did not wake an individual from sleep.]
BRIP1 Gene Mutation	NCIT_C132002	[A change in the nucleotide sequence of the BRIP1 gene.]
BRIP1 Gene	NCIT_C63526	[This gene is involved in DNA double-strand break repair.]
FANCF Gene Mutation	NCIT_C132003	[A change in the nucleotide sequence of the FANCF gene.]
FANCF Gene	NCIT_C86553	[This gene may be involved in the regulation of DNA repair.]
Increased Drug AUC	NCIT_C54605	[Increased area under the plot of plasma concentration of a drug against time after drug administration.]
Rectal Perforation, CTCAE 5.0	NCIT_C146634	[A disorder characterized by a rupture in the rectal wall.]
Decreased Peak Drug Blood Concentration	NCIT_C54606	[Decreased maximum (peak) concentration of a drug observed after its administration.]
Decreased Drug Half Life	NCIT_C54607	[Decreased period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.]
IL-2/9/15 Gamma Chain Receptor Inhibitor BNZ-1	NCIT_C146636	[A pegylated peptide antagonist that binds to the common gamma chain (gc; IL2RG; CD132) of the signaling receptor for the pro-inflammatory cytokines interleukin (IL)-2, IL-9, and IL-15, with potential immunomodulating and antineoplastic activities. Upon administration, IL-2/9/15 gc receptor inhibitor BNZ-1 specifically targets and binds to the IL binding site on the gc receptor and blocks IL-2, IL-9 and IL-15 binding, thereby inhibiting IL-2-, IL-9-, and IL-15-mediated signaling and downstream pathways. This may inhibit proliferation of tumor cells that are dependent on IL-2/9/15 signaling for their growth. IL-2/9/15 are upregulated in certain tumor cell types and play a key role in tumor progression and survival.]
Decreased Time To Peak Drug Blood Concentration	NCIT_C54608	[Decreased time following drug administration at which the peak drug blood concentration occurs.]
Decreased Drug AUC	NCIT_C54609	[Decreased area under the plot of plasma concentration of a drug against time after drug administration.]
Calcineurin inhibitor	NCIT_C146638	[Any agent that inhibits calcineurin (protein phosphatase 3; PPP3), a serine/threonine protein phosphatase dependent on calcium and calmodulin, with immunosuppressant activity. Inhibition of calcineurin prevents dephosphorylation of the transcription factor nuclear factor of activated T-cells, cytoplasmic (NFATc), which prevents its translocation to the nucleus and the subsequent induction of the expression of interleukin-2 (IL-2). This prevents IL-2-mediated proliferation and activation of T-cells, and T-lymphocyte-mediated immune responses.]
English Fancier before 1929	NCIT_C15030
Zellweger Spectrum Disorder	NCIT_C146639	[A group of conditions with overlapping signs and symptoms. It includes Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease.]
Peroxisome Biogenesis Disorder	NCIT_C155747	[A group of conditions characterized by impairment of peroxisome assembly and metabolic pathways confined to this organelle, caused by mutation(s) in the peroxin (PEX) gene family. Phenotypically, they manifest as Zellweger syndrome (ZS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and rhizomelic chondrodysplasia punctata (RCDP1), the latter a distinct peroxisome biogenesis disorder phenotype. ZS, NALD, and IRD have multiple complementation groups and form a spectrum of diseases with overlapping features.]
DW/J Mouse	NCIT_C15031
C-SSRS Already Enrolled Subjects - Description of Actual Suicide Attempt	NCIT_C107060	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Description of actual attempt.]
HG Goodale	NCIT_C15032
C-SSRS Already Enrolled Subjects - Non-suicidal Self-injurious Behavior (Prior to Study Entry)	NCIT_C107061	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Has subject engaged in non-suicidal self-injurious behavior? (Prior to Study Entry).]