Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
SOSTDC1 wt Allele	NCIT_C132098	[Human SOSTDC1 wild-type allele is located in the vicinity of 7p21.2 and is approximately 69 kb in length. This allele, which encodes sclerostin domain-containing protein 1, plays a role in the modulation of bone morphogenic protein-dependent signaling pathways.]
7p21.2	NCIT_C39916	[A chromosome band present on 7p]
Sclerostin Domain-Containing Protein 1	NCIT_C132099	[Sclerostin domain-containing protein 1 (206 aa, ~23 kDa) is encoded by the human SOSTDC1 gene. This protein is involved in the inhibition of bone morphogenic proteins.]
Collecting Tube	NCIT_C32344	[The final section of a renal tubule in the nephron between the distal convoluted tubule and the ureter comprising of principal and intercalated cells. The collecting tube acts to reabsorb sodium and water while secreting potassium and maintaining acid-base homeostasis.]
USP14 Gene	NCIT_C132090	[This gene is involved in ubiquitin recycling.]
Cysteine Peptidase Gene	NCIT_C28404	[Cysteine Protease Genes encode endopeptidases, inactivated by sulfhydryl reagents, that have a cysteine residue involved in the catalytic process. (NCI)]
USP14 wt Allele	NCIT_C132091	[Human USP14 wild-type allele is located in the vicinity of 18p11.32 and is approximately 56 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 14 protein, plays a role in the removal of ubiquitin from protein substrates.]
18p11.32	NCIT_C13966	[A chromosome band present on 18p]
Ubiquitin Carboxyl-Terminal Hydrolase 14	NCIT_C132092	[Ubiquitin carboxyl-terminal hydrolase 14 (494 aa, ~56 kDa) is encoded by the human USP14 gene. This protein is involved in the regulation of both ubiquitinated protein degradation and endoplasmic reticulum-associated degradation.]
Cysteine Proteinase	NCIT_C16481	[An enzyme that contains an unpaired cysteine in the active site which acts as a nucleophilic thiol to catalyze the proteolytic processing of other proteins or polypeptides.]
HOXA5 Gene	NCIT_C132093	[This gene plays a role in the regulation of gene transcription during embryogenesis.]
HOXA Gene Family	NCIT_C105821	[A family of genes found in a cluster on the p arm of chromosome 7. These genes encode transcription factors that play a role in gene expression, morphogenesis, and cell differentiation.]
HOXA5 wt Allele	NCIT_C132094	[Human HOXA5 wild-type allele is located in the vicinity of 7p15.2 and is approximately 3 kb in length. This allele, which encodes homeobox protein Hox-A5, is involved in transcriptional regulation.]
7p15.2	NCIT_C73640	[A chromosome band present on 7p]
Intramuscular Lipoma	NCIT_C7450	[A benign tumor, composed of mature adipocytes, that arises within skeletal muscle fibers.]
Deep Lipoma	NCIT_C6498	[A benign well-circumscribed tumor, composed of mature adipocytes, that arises within deep soft tissues.]
Infiltrating Lipoma	NCIT_C7451	[A benign tumor, composed of lobules of mature adipocytes, that penetrates the surrounding tissue from which it arises. There is usually a higher local recurrence rate when compared with non-infiltrating lipomas.]
Odontogenic Myxofibroma	NCIT_C7452	[An intraosseous odontogenic neoplasm with good prognosis, arising from the mandible and less frequently from the maxilla. It is characterized by the presence of stellate cells, myxoid stroma formation, and prominent collagen. Small tumors may be cured with enucleation. Complete excision may be required for larger tumors.]
Exocervical Carcinoma	NCIT_C7453	[A carcinoma that arises from the squamous epithelium of the exocervix.]
Malignant Exocervical Neoplasm	NCIT_C3554	[A malignant neoplasm that affects the exocervix.]