Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Serine	NCIT_C29613	[A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)]
Low Grade Glioma	NCIT_C132067	[A grade I or grade II glioma arising from the central nervous system. This category includes pilocytic astrocytoma, diffuse astrocytoma, subependymal giant cell astrocytoma, ependymoma, oligodendroglioma, oligoastrocytoma, and angiocentric glioma.]
Glioma	NCIT_C3059	[A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas.]
Epidermal Growth Factor Receptor Kinase Pathway Substrate 8-Like Protein 3	NCIT_C29614	[Epidermal growth factor receptor kinase substrate 8-like protein 3 (593 aa, ~67 kDa) is encoded by the human EPS8L3 gene. This protein may be involved in the regulation of son of sevenless homolog 1-mediated guanine exchange activity.]
Metastasis Protein	NCIT_C54671	[Normal proteins that, when altered or inappropriately expressed, contribute to the spread or migration of cancer cells from one part of the body (i.e., the location of the primary tumor) to another.]
Cytoreduction Treatment	NCIT_C155678	[Any therapy designed to reduce the number of cells of a particular type or in a particular location.]
Fatty Acid-Binding Protein, Liver	NCIT_C29615	[Fatty acid-binding protein, liver (127 aa, ~14 kDa) is encoded by the human FABP1 gene. This protein is involved in binding to bilirubin, and fatty acids and their acetyl coenzyme A derivatives.]
Peritonectomy	NCIT_C132069	[A surgical procedure that refers to the removal of the peritoneal sites affected by cancer.]
Alanine	NCIT_C29605	[A small non-essential amino acid in humans, Alanine is one of the most widely used for protein construction and is involved in the metabolism of tryptophan and vitamin pyridoxine. Alanine is an important source of energy for muscles and central nervous system, strengthens the immune system, helps in the metabolism of sugars and organic acids, and displays a cholesterol-reducing effect in animals. (NCI04)]
Arginine Hydrochloride	NCIT_C29606	[The hydrochloride salt form of arginine, an essential amino acid in juvenile humans. Arginine is a complex amino acid, often found at active sites in proteins and enzymes due to its amine-containing side chain. Arginine may prevent or treat heart and circulatory diseases, combat fatigue, and stimulate the immune system. It also boosts production of nitric oxide, relaxing blood vessels, and treating angina and other cardiovascular problems. Arginine is also an important intermediate in the urea cycle and in detoxification of nitrogenous wastes. (NCI04)]
Asparagine	NCIT_C29607	[A non-essential amino acid in humans, Asparagine is a beta-amido derivative of aspartic acid and plays an important role in the biosynthesis of glycoproteins and other proteins. A metabolic precursor to aspartate, Asparagine is a nontoxic carrier of residual ammonia to be eliminated from the body. Asparagine acts as diuretic. (NCI04)]
Aspartic Acid	NCIT_C29608	[A non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. Aspartic acid also serves as a neurotransmitter. (NCI04)]
Cysteine	NCIT_C29609	[A non-essential sulfur-containing amino acid in humans, related to cystine, Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found in beta-keratin, the main protein in nails, skin, and hair, Cysteine is important in collagen production, as well as skin elasticity and texture. Also required in the manufacture of amino acid taurine, Cysteine is a component of the antioxidant glutathione, and plays a role in the metabolism of essential biochemicals such as coenzyme A, heparin, and biotin. (NCI04)]
C-SSRS Already Enrolled Subjects - Most Recent Suicide Attempt Date	NCIT_C107080	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Most recent attempt date.]
C-SSRS Already Enrolled Subjects - Most Recent Suicide Attempt Actual Lethality/Medical Damage	NCIT_C107081	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Most recent attempt actual lethality/medical damage.]
Activating TSHR Gene Mutation	NCIT_C132060	[Mutation(s) in the TSHR gene resulting in increased function of the thyroid stimulating hormone receptor.]
TSHR Gene Mutation	NCIT_C131021	[A change in the nucleotide sequence of the TSHR gene.]
C-SSRS Already Enrolled Subjects - Most Recent Suicide Attempt Potential Lethality	NCIT_C107082	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Most recent attempt potential lethality.]
Inactivating TSHR Gene Mutation	NCIT_C132061	[Mutation(s) in the TSHR gene, resulting in decreased function of the thyroid stimulating hormone receptor.]
C-SSRS Already Enrolled Subjects - Most Lethal Suicide Attempt Date	NCIT_C107083	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Most lethal attempt date.]