Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Affinity	NCIT_C20604	[The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex.]
Developmental Anatomy	NCIT_C20605	[The branch of anatomy concerned with the structural changes that take place between fertilization and maturity.]
Anatomical Sciences	NCIT_C16287	[The science concerned with the physical structure of animals and plants.]
Catchment Area	NCIT_C20606	[Catchment Area refers to the geographic area, and thus the population of individuals who qualify for consideration or inclusion in a study.]
Arteriogram	NCIT_C20607
DR1 Gene	NCIT_C20600	[This gene is involved in repression of transcription.]
B-TFIID Subunit Gene	NCIT_C20602	[Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP) and TBP-associated factors, or TAFs, in 2 distinct complexes, TFIID and B-TFIID. The majority of TBP is present in the B-TFIID complex, which is composed of TBP and BTAF1. Stable association of TBP and BTAF1 requires the presence of DNA. BTAF1 inhibits TBP-driven RNA polymerase II and III transcription by driving the dissociation of TBP from DNA and freeing the TBP to associate with other TATA boxes or TATA-less promoters. (from OMIM 605191, LocusID 9044)]
BTAF1 Gene	NCIT_C20603	[This gene is involved in transcription initiation and transcriptional regulation.]
Granzyme	NCIT_C20619	[A family of serine endopeptidases. Members of this family are stored in the granules of cytotoxic T cells. Upon release of the granules, these enzymes enter infected cells where they can proteolytically stimulate caspase activation and initiate apoptosis.]
Serine Protease	NCIT_C17123	[Proteases that have a serine residue in the active center of the enzyme. These enzymes catalyze the hydrolysis of covalent peptidic bonds by serine nucleophilic attack. Serine proteases participate in a wide range of functions in the body, including blood clotting, inflammation, and digestion.]
Cancer Family	NCIT_C20615	[A group of blood relatives of whom several have had cancer; the mode of aggregation may be genetic and homogeneous, as in familial polyposis of the colon; diverse as in neurofibromatosis; or due to common exposure to a carcinogenic or oncogenic agent, such as a virus.]
Family	NCIT_C25173	[A domestic group, or a number of domestic groups linked through descent (demonstrated or stipulated) from a common ancestor, marriage, or adoption.]
Recombination Fraction	NCIT_C20616	[The percentage of individuals in a population with a non-parental genotype.]
Housekeeping Gene	NCIT_C20617	[Genes that are expressed at a fairly consistent level throughout the cell cycle and from tissue to tissue. Usually involved in routine cellular metabolism. Often used for comparison when studying expression of other genes of interest.]
Quantitative Genetics	NCIT_C20618	[The branch of genetics concerned with the inheritance of continuously-varying traits.]
Genetics	NCIT_C16624	[The branch of biology that deals with heredity, especially the mechanisms of hereditary transmission and the variation of inherited characteristics among similar or related organisms]
Cytopathology	NCIT_C20611	[A branch of pathology that studies and diagnoses diseases on the cellular level including the anatomy, physiology, pathology and chemistry of the cell.]
Pathology	NCIT_C18189	[The medical science, and specialty practice, concerned with all aspects of disease, but with special reference to the essential nature, causes, and development of abnormal conditions, as well as the structural and functional changes that result from the disease processes. Informally used to mean the result of such an examination.]
Clonal Expansion	NCIT_C20613	[Multiplication or reproduction by cell division of a population of identical cells descended from a single progenitor. In immunology, may refer to the clonal proliferation of cells responsive to a specific antigen as part of an immune response. (NCI)]
Primer Extension	NCIT_C20614	[A method to synthesize cDNA for determining the 5'-untranslated region of a specific mRNA molecule through reverse transcription reaction using complementary oligonucleotides as primers.]