Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Guaifenesin/Codeine	NCIT_C29082	[A combination preparation containing guaifenesin and the opioid agonist codeine with expectorant and antitussive activities, respectively. Guaifenesin works by drawing water into respiratory tracts, by which reducing adhesiveness and surface tension of mucus as well as increasing hydration of mucus, thereby reducing the viscosity of mucus and making cough more productive. Codeine, a naturally occurring phenanthrene alkaloid and opioid agonist mimics the actions of opioids by binding to the opioid receptors at many sites within the central nervous system (CNS), thereby also suppressing the cough reflex by activating receptors in the cough center.]
Adult Ependymal Tumor	NCIT_C68690	[An ependymal tumor of the central nervous system occurring in adults.]
Ependymal Tumor	NCIT_C6770	[A group of neoplasms which arise from the ependymal lining of the cerebral ventricles and from the remnants of the central canal of the spinal cord. Ependymal tumors occur predominantly in children and young adults with varied morphological features and biological behavior. There are 4 types: ependymoma, anaplastic ependymoma, myxopapillary ependymoma and subependymoma. (WHO)]
HuCC49deltaCH2-PA-DOTA	NCIT_C29095	[An immunoconjugate comprised of a humanized monoclonal antibody with antitumor activity. The monoclonal antibody CC49 is developed from the murine monoclonal antibody B72.3 and is humanized by grafting the hypervariable regions onto the variable light (VL) and variable heavy (VH) frameworks of the monoclonal antibodies LEN and 21/28' CL. In addition the CH2 domain in the constant region is deleted to increase plasma clearance. The resultant antibody binds to the pancarcinoma tumor-associated glycoprotein (TAG)-72 with high affinity. Furthermore, the antibody is conjugated to PA-DOTA, a bifunctional chelating agent and commonly radiolabeled, resulting in an effective agent for radioimmunotherapy.]
Conjugated Monoclonal Antibody CC49	NCIT_C2747	[A immunoconjugate comprised of a monoclonal antibody directed against the pancarcinoma antigen TAG-72.conjugated to PA-DOTA, a bifunctional chelant. TAG-72 is a protein/sugar complex found on the surface of many cancer cells, including breast, colon, and pancreatic cancer cells. (NCI04)]
Device Evaluation Conclusion	NCIT_C54030
Device Evaluation	NCIT_C53648
Hycaptmn	NCIT_C29096
Missing	NCIT_C54031	[Not existing; not able to be found.]
Hydrazine	NCIT_C29097	[A highly reactive base and reducing agent used in many industrial and medical applications. In biological applications, hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine. In psychiatry, the use of hydrazine derivatives is limited due to the emergence of the tricyclic antidepressants. (NCI04)]
Anticachexia Agent	NCIT_C1935	[Drugs which reduce the fatigue and weight loss often associated with cancer.]
Other Asian	NCIT_C107601	[A person having origins in the original peoples of Asia, but not China, India, Korea, the Philippine Islands or Vietnam.]
Verbatim	NCIT_C54032	[In precisely the same words used by a writer or speaker.]
Hydrochlorothiazide	NCIT_C29098	[A short acting thiazide diuretic. Hydrochlorothiazide (HCTZ) is widely used to treat hypertension and edema. This agent's metabolite appears to preferentially bind to and accumulate in red blood cells. This agent is primarily excreted by the kidneys.]
Other Pacific Islander	NCIT_C107602	[A person having origins in the original peoples of the Pacific Islands, but not Guam, Hawaii, the Mariana Islands or Samoa.]
Native Hawaiian or Other Pacific Islander	NCIT_C41219	[A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands. (OMB)]
Conclusion	NCIT_C54033	[A position or opinion or judgment reached after consideration.]
Hydrocodone Bitartrate	NCIT_C29099	[The bitartrate salt form of hydrocodone, a semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.]
FGFR2 NM_000141.4:c.1645A>C	NCIT_C107603	[A nucleotide substitution at position 1645 of the coding sequence of the FGFR2 gene where cytosine has been mutated to guanine.]
FGFR2 NP_000132.3:p.N549H	NCIT_C107604	[A change in the amino acid residue at position 549 in the fibroblast growth factor receptor 2 protein where asparagine has been replaced by histidine.]