Terminology Service < Semantic Lookup Platform

All terms in ONE

Label	Id	Description
recombinant vector	OBI_0000731	[A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.]
recombinant vector cloning	OBI_0600064	[a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material]
organism	OBI_0100026	[A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.]
intracellular cytokine staining assay measuring epitope specific interleukin-17A production by T cells	OBI_0001589	[A T cell epitope specific interleukin-17A production assay that uses an intracellular cytokine staining assay.]
cell culture supernatant	OBI_1000023	[Supernatant of a cell culture is a material entity which contains media, supplements, and secreted products of the cells and becomes the environment of cultivated cell.]
culture medium	OBI_0000079	[a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.]
isolation of cell culture supernatant	OBI_0600029	[a protocol which results in the separation of supernatant material from a cell culture]
sodium phosphate	CHEBI_37586
cell pellet	OBI_1000024	[A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension]
centrifugation	OBI_0302886	[centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation]
material transport service	OBI_0001580	[A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer.]
DNA extraction	OBI_0000257	[A DNA extraction is a nucleic acid extraction where the desired output material is DNA.]
deoxyribonucleic acid	CHEBI_16991	[High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.]
equilibrium dissociation constant (KD) approximated by EC50	OBI_0001581	[A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, and the concentration of the receptor must be much less than the KD for the ligand. ]
half maximal effective concentration (EC50)	OBI_0001180	[half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time. ]
obsolete cell bound MHC direct binding assay	OBI_0001582	[direct binding assay measuring MHC ligand binding using MHC derived from a cell]
half life of binding datum	OBI_0001583	[A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association. ]
half life datum (t 1/2)	OBI_0001171	[The time it takes for 50% of a class of stochastic processes to occur. ]
purified MHC direct binding assay measuring binding of a MHC:ligand complex using phage display	OBI_0001584	[A purified MHC binding assay that uses a phage display binding assay to measure direct ligand binding.]
phage display binding assay	OBI_0001476	[A binding assay in which a collection of phages expressing a library of different peptides or protein fragnments is used to infect cells, followed by screening for cells that bind a protein of interest, and identifiying the sequence of infecting phages to determine a suitable binding partner.]