Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Grik3	rgd:71027	[ENCODES a protein that exhibits glutamate receptor activity; ionotropic glutamate receptor activity; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity (ortholog); INVOLVED IN negative regulation of synaptic transmission, glutamatergic; regulation of membrane potential; G protein-coupled glutamate receptor signaling pathway (ortholog); PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); lung small cell carcinoma (ortholog); FOUND IN axon; dendrite; dendrite cytoplasm; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol]
Adh4	rgd:71028	[ENCODES a protein that exhibits alcohol dehydrogenase (NAD+) activity; ethanol binding; NAD binding; INVOLVED IN aging; ethanol oxidation; ovulation cycle; PARTICIPATES IN fatty acid metabolic pathway; gluconeogenesis pathway; glycolysis pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); non-alcoholic fatty liver disease (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine]
Ip6k1	rgd:71025	[ENCODES a protein that exhibits inositol hexakisphosphate kinase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); phosphatidylinositol phosphorylation (ortholog); PARTICIPATES IN inositol phosphate metabolic pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); fibrillar center (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol 3-benzoate; 2,6-dinitrotoluene]
Rpsa	rgd:71026	[ENCODES a protein that exhibits laminin binding (ortholog); ribosome binding (ortholog); INVOLVED IN cell-cell adhesion; epithelial cell differentiation; PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH irritable bowel syndrome; sciatic neuropathy; Spinal Cord Injuries; FOUND IN basement membrane; collagen-containing extracellular matrix; cytoplasm; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol]
LOC685199	rgd:1597684
Col3a1	rgd:71029	[ENCODES a protein that exhibits extracellular matrix structural constituent (ortholog); integrin binding (ortholog); platelet-derived growth factor binding (ortholog); INVOLVED IN response to mechanical stimulus; skeletal system development; aorta smooth muscle tissue morphogenesis (ortholog); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; ASSOCIATED WITH bladder neck obstruction; Contracture; glomerulosclerosis; FOUND IN collagen-containing extracellular matrix; collagen trimer (ortholog); collagen type III trimer (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-noradrenaline; 1-naphthyl isothiocyanate]
LOC100909755	rgd:6502059
LOC102549628	rgd:7541987
Psme1-ps1	rgd:1597686	[FOUND IN proteasome activator complex (inferred)]
LOC687676	rgd:1583031
Lman1	rgd:71020	[ENCODES a protein that exhibits identical protein binding; INVOLVED IN endoplasmic reticulum organization (ortholog); Golgi organization (ortholog); positive regulation of organelle organization (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; protein secretory pathway; ASSOCIATED WITH factor V deficiency (ortholog); factor XIII deficiency (ortholog); Familial Multiple Coagulation Factor Deficiency I (ortholog); FOUND IN endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-methoxyethanol]
Dctn4	rgd:71023	[ENCODES a protein that exhibits protein N-terminus binding (ortholog); PARTICIPATES IN mitochondria transport pathway; Huntington's disease pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH cystic fibrosis (ortholog); Hereditary Neoplastic Syndromes (ortholog); Pseudomonas Infections (ortholog); FOUND IN cytoplasmic dynein complex; focal adhesion; kinetochore; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A]
Actr3	rgd:71024	[ENCODES a protein that exhibits actin binding; ATPase binding; actin filament binding (ortholog); INVOLVED IN astrocyte differentiation; cellular response to epidermal growth factor stimulus; cellular response to interleukin-1; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH increased urine protein level; ASSOCIATED WITH Cognitive Dysfunction; focal segmental glomerulosclerosis; schizophrenia; FOUND IN actin filament; apical ectoplasmic specialization; apical tubulobulbar complex; INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine]
Parva	rgd:71021	[ENCODES a protein that exhibits protein-containing complex binding; actin binding (ortholog); INVOLVED IN actin cytoskeleton organization; actin-mediated cell contraction (ortholog); cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN protein-containing complex; actin cytoskeleton (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; ammonium chloride]
Itga7	rgd:71022	[ENCODES a protein that exhibits cell adhesion molecule binding; integrin binding; laminin binding; INVOLVED IN cell adhesion; integrin-mediated signaling pathway; skeletal muscle tissue development; PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; hypertrophic cardiomyopathy pathway; ASSOCIATED WITH arteriosclerosis; cardiomyopathy; Colonic Neoplasms (ortholog); FOUND IN cell surface; integrin complex; cytoplasm (ortholog); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene]
Gdf9	rgd:71038	[ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN blastocyst development (ortholog); embryonic cleavage (ortholog); negative regulation of cell growth (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); mitochondrial complex III deficiency (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 3-methylcholanthrene]
Mgll	rgd:71039	[ENCODES a protein that exhibits acylglycerol lipase activity; hydrolase activity; protein homodimerization activity (ortholog); INVOLVED IN monoacylglycerol catabolic process; negative regulation of blood vessel diameter; acylglycerol catabolic process (ortholog); PARTICIPATES IN glycerolipid metabolic pathway; ASSOCIATED WITH amenorrhea (ortholog); osteoporosis (ortholog); FOUND IN synapse; axon (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine]
Mepe	rgd:71036	[INVOLVED IN regulation of bone remodeling; negative regulation of bone mineralization (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride]
Prlhr	rgd:71037	[ENCODES a protein that exhibits G protein-coupled receptor activity; peptide hormone binding; INVOLVED IN feeding behavior; G protein-coupled receptor signaling pathway; hormone metabolic process (ortholog); PARTICIPATES IN obesity pathway; ASSOCIATED WITH obese; polyphagia; ASSOCIATED WITH obesity; hypertension (ortholog); FOUND IN cilium (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; ammonium chloride; bexarotene]
Sall4	rgd:1597672	[ENCODES a protein that exhibits transcription factor binding (ortholog); INVOLVED IN embryonic limb morphogenesis (ortholog); heart development (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Congenital Limb Deformities (ortholog); Craniofacial Abnormalities (ortholog); Duane retraction syndrome (ortholog); FOUND IN heterochromatin (ortholog); intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog)]