Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Erbb3	rgd:69323	[ENCODES a protein that exhibits neuregulin binding; neuregulin receptor activity; ErbB-3 class receptor binding (ortholog); INVOLVED IN axonogenesis; cellular response to insulin stimulus; circadian rhythm; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; angiotensin II signaling pathway via AT2 receptor; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH chronic obstructive pulmonary disease; median neuropathy; Mouth Neoplasms; FOUND IN nucleus; postsynaptic membrane; apical part of cell (ortholog); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; aldehydo-D-glucose]
Ogfr	rgd:69324	[ENCODES a protein that exhibits opioid receptor activity (inferred); INVOLVED IN opioid receptor signaling pathway (inferred); regulation of growth (inferred); ASSOCIATED WITH epilepsy (ortholog); FOUND IN membrane (inferred); nucleus (inferred); perinuclear region of cytoplasm (inferred); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride]
LOC103692908	rgd:9226732
Cyp11a1	rgd:69325	[ENCODES a protein that exhibits cholesterol binding; cholesterol monooxygenase (side-chain-cleaving) activity; heme binding (ortholog); INVOLVED IN biphenyl metabolic process; C21-steroid hormone biosynthetic process; cellular response to antibiotic; PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH Brain Injuries; Cardiomegaly; Diabetes Mellitus, Experimental ; FOUND IN mitochondrial crista; mitochondrial inner membrane; mitochondrion; INTERACTS WITH (+)-pilocarpine; (-)-citrinin; (S)-nicotine]
Arl2	rgd:69326	[ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN acetylcholine transport; bicellular tight junction assembly (ortholog); centrosome cycle (ortholog); ASSOCIATED WITH malignant glioma (ortholog); melanoma (ortholog); FOUND IN cytoplasm; cytosol; Golgi apparatus; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A]
Arl3	rgd:69327	[ENCODES a protein that exhibits GDP binding; GTP binding; GTPase activating protein binding (ortholog); INVOLVED IN cilium assembly (ortholog); Golgi to plasma membrane transport (ortholog); intraciliary transport (ortholog); ASSOCIATED WITH autosomal recessive polycystic kidney disease (ortholog); JOUBERT SYNDROME 35 (ortholog); retinitis pigmentosa 2 (ortholog); FOUND IN axoneme (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride]
Cdkn1a	rgd:69328	[ENCODES a protein that exhibits protein-containing complex binding; cyclin binding (ortholog); cyclin-dependent protein kinase activating kinase activity (ortholog); INVOLVED IN animal organ regeneration; cellular response to heat; intestinal epithelial cell maturation; PARTICIPATES IN G1/S transition pathway; Notch signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; ASSOCIATED WITH autosomal dominant polycystic kidney disease; Brain Injuries; Diabetes Mellitus, Experimental ; FOUND IN cytoplasm; nucleus; perinuclear region of cytoplasm; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (S)-colchicine]
Sf3b6	rgd:2318878	[ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN blastocyst formation (ortholog); mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN nucleus (ortholog); U12-type spliceosomal complex (ortholog); INTERACTS WITH tolcapone; (S)-nicotine (ortholog); 2-hydroxypropanoic acid (ortholog)]
Mapt	rgd:69329	[ENCODES a protein that exhibits chaperone binding; enzyme binding; heat shock protein binding; INVOLVED IN apoptotic process; brain development; female pregnancy; PARTICIPATES IN Reelin signaling pathway; Alzheimer's disease pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Alzheimer's disease; Brain Injuries, Traumatic; brain ischemia; FOUND IN axon; axonal growth cone; cytoplasm; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,5-hexanedione]
LOC102549116	rgd:7526978
Lcn5	rgd:69320	[ENCODES a protein that exhibits small molecule binding (inferred); FOUND IN extracellular region (inferred)]
Hadh	rgd:69321	[ENCODES a protein that exhibits 3-hydroxyacyl-CoA dehydrogenase activity; INVOLVED IN fatty acid beta-oxidation; negative regulation of insulin secretion; response to activity; PARTICIPATES IN fatty acid beta degradation pathway; 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; myocardial infarction; obesity; FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-adrenaline; 1-naphthyl isothiocyanate]
Gucy2e	rgd:69322	[ENCODES a protein that exhibits guanylate cyclase activity; natriuretic peptide receptor activity; INVOLVED IN cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; PARTICIPATES IN purine metabolic pathway; visual phototransduction pathway; FOUND IN integral component of membrane; non-motile cilium; plasma membrane]
LOC100365502	rgd:2318880
Cpa3	rgd:2390	[ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN regulation of angiotensin levels in blood (ortholog); PARTICIPATES IN renin-angiotensin cascade pathway; FOUND IN transport vesicle (inferred); INTERACTS WITH 17beta-estradiol; ammonium chloride; bisphenol A]
LOC102547768	rgd:7703064
Cpb1	rgd:2391	[ENCODES a protein that exhibits carboxypeptidase activity; INVOLVED IN proteolysis (ortholog); INTERACTS WITH aflatoxin B1; ammonium chloride; bis(2-ethylhexyl) phthalate]
Cpd	rgd:2393	[ENCODES a protein that exhibits protein phosphatase 2A binding; protein-containing complex binding; metallocarboxypeptidase activity (ortholog); INVOLVED IN cellular response to interleukin-2; proteolysis (ortholog); FOUND IN intracellular membrane-bounded organelle; nucleus; perinuclear region of cytoplasm; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Cpe	rgd:2394	[ENCODES a protein that exhibits carboxypeptidase activity; cobalt ion binding; protein domain specific binding; INVOLVED IN enkephalin processing; insulin processing; negative regulation of branching morphogenesis of a nerve; PARTICIPATES IN melanocortin system pathway; type 1 diabetes mellitus pathway; ASSOCIATED WITH endocrine system disease (ortholog); Insulin Resistance (ortholog); Lung Neoplasms (ortholog); FOUND IN dendrite; dense core granule; extracellular region; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 3,7-dihydropurine-6-thione]
LOC102547600	rgd:7703068