Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Axin2	rgd:69259	[ENCODES a protein that exhibits beta-catenin binding; protein kinase binding; enzyme binding (ortholog); INVOLVED IN cell death; cellular response to organic cyclic compound; negative regulation of cell population proliferation; PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Animal Disease Models (ortholog); anodontia (ortholog); colon carcinoma (ortholog); FOUND IN protein-containing complex; centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine]
Wnt5a	rgd:69250	[ENCODES a protein that exhibits chemoattractant activity involved in axon guidance (ortholog); cytokine activity (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell differentiation; estrous cycle; lung alveolus development; PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH autosomal dominant Robinow syndrome 1 (ortholog); endometrial carcinoma (ortholog); Female Urogenital Diseases (ortholog); FOUND IN cytoplasm; extracellular space; cell surface (ortholog); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol]
LOC108348405	rgd:11479443
Hpgds	rgd:69251	[ENCODES a protein that exhibits calcium ion binding (ortholog); magnesium ion binding (ortholog); prostaglandin-D synthase activity (ortholog); INVOLVED IN negative regulation of male germ cell proliferation (ortholog); prostaglandin metabolic process (ortholog); PARTICIPATES IN prostaglandin biosynthetic pathway; arachidonic acid metabolic pathway; eicosanoid metabolic pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Kidney Neoplasms (ortholog); liver disease (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione]
Ier5	rgd:69252	[ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cellular response to heat (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil]
Pitx1	rgd:69253	[ENCODES a protein that exhibits DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN regulation of transcription, DNA-templated; branchiomeric skeletal muscle development (ortholog); cartilage development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); clubfoot (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); transcription factor complex (ortholog); INTERACTS WITH 7,12-dimethyltetraphene; all-trans-retinoic acid; ammonium chloride]
Impa1	rgd:69254	[ENCODES a protein that exhibits inositol monophosphate 1-phosphatase activity; inositol monophosphate phosphatase activity; lithium ion binding; INVOLVED IN inositol phosphate dephosphorylation; phosphatidylinositol biosynthetic process; response to lithium ion; PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH Mental Retardation, Autosomal Recessive 59 (ortholog); visual epilepsy (ortholog); FOUND IN axon; neuronal cell body; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene]
Hnrnpab	rgd:69255	[ENCODES a protein that exhibits protein-containing complex binding; sequence-specific double-stranded DNA binding; transcription factor binding; INVOLVED IN cellular response to amino acid stimulus; regulation of cellular localization; regulation of intracellular mRNA localization; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH transient cerebral ischemia; hepatocellular carcinoma (ortholog); Mammary Neoplasms, Experimental (ortholog); FOUND IN dendrite; messenger ribonucleoprotein complex; neuronal ribonucleoprotein granule; INTERACTS WITH (S)-AMPA; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol]
Slc24a3	rgd:69256	[ENCODES a protein that exhibits calcium, potassium:sodium antiporter activity; INVOLVED IN cation transport; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN plasma membrane; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol]
LOC103690344	rgd:9212267
LOC103693908	rgd:9432960
Gpx3	rgd:69224	[ENCODES a protein that exhibits glutathione peroxidase activity; selenium binding; identical protein binding (ortholog); INVOLVED IN glutathione metabolic process; hydrogen peroxide catabolic process; response to corticosterone; PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; endometrial adenocarcinoma; lung disease; FOUND IN extracellular space; INTERACTS WITH 17beta-estradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine]
Hgs	rgd:69225	[ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); ubiquitin-dependent protein binding (ortholog); INVOLVED IN endosome to lysosome transport; membrane invagination (ortholog); negative regulation of angiogenesis (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor signaling pathway; endocytosis pathway; FOUND IN cytosol; membrane; secretory granule; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene]
Gpx4	rgd:69226	[ENCODES a protein that exhibits glutathione peroxidase activity; phospholipid-hydroperoxide glutathione peroxidase activity; selenium binding; INVOLVED IN aging; glutathione metabolic process; regulation of inflammatory response; PARTICIPATES IN glutathione metabolic pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Cadmium Poisoning (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nuclear envelope (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene]
Gpx5	rgd:69227	[ENCODES a protein that exhibits glutathione peroxidase activity (inferred); INVOLVED IN cellular response to oxidative stress (ortholog); PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; FOUND IN extracellular space (ortholog); sperm plasma membrane (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cadmium atom]
Cxxc4	rgd:69228	[ENCODES a protein that exhibits PDZ domain binding; methyl-CpG binding (ortholog); zinc ion binding (ortholog); INVOLVED IN negative regulation of Wnt signaling pathway (ortholog); Wnt signaling pathway (ortholog); PARTICIPATES IN Wnt signaling pathway; FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride]
Rack1	rgd:69229	[ENCODES a protein that exhibits protein kinase C binding; BH3 domain binding (ortholog); cyclin binding (ortholog); INVOLVED IN negative regulation of translation; regulation of protein localization to plasma membrane; activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; insulin-like growth factor signaling pathway; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH transient cerebral ischemia; Mouth Neoplasms (ortholog); squamous cell carcinoma (ortholog); FOUND IN small ribosomal subunit; cell body (ortholog); cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
LOC108353808	rgd:11480409
LOC103692956	rgd:9212274
Kcnq3	rgd:69222	[ENCODES a protein that exhibits calmodulin binding; ion channel binding; protein kinase binding; INVOLVED IN cellular response to ammonium ion; ganglion development; ion transmembrane transport; ASSOCIATED WITH Hyperalgesia; autistic disorder (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN axon initial segment; cell surface; dendrite; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil]