Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Psg19	rgd:2334	[INVOLVED IN female pregnancy]
Chad	rgd:2336	[INVOLVED IN cartilage condensation; bone development (ortholog); negative regulation of bone trabecula formation (ortholog); PARTICIPATES IN cell-extracellular matrix signaling pathway; FOUND IN extracellular matrix (inferred); integral component of membrane (inferred); INTERACTS WITH 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil; ammonium chloride]
LOC102549326	rgd:7644068
LOC102557085	rgd:7644069
Chga	rgd:2338	[INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation; negative regulation of blood vessel diameter; negative regulation of neuron death; PARTICIPATES IN G protein mediated signaling pathway; ASSOCIATED WITH hypertension; end stage renal failure (ortholog); IgA glomerulonephritis (ortholog); FOUND IN chromaffin granule; extracellular space; neuronal dense core vesicle; INTERACTS WITH (S)-nicotine; 6-propyl-2-thiouracil; ammonium chloride]
LOC102552709	rgd:7742486
LOC108349776	rgd:11455558
LOC108350294	rgd:11479502
LOC103695243	rgd:9344023
LOC103693169	rgd:9261214
Chm	rgd:2340	[ENCODES a protein that exhibits protein-containing complex binding; Rab GTPase binding; INVOLVED IN protein geranylgeranylation; protein-containing complex assembly; blood vessel development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Choroideremia (ortholog); eye disease (ortholog); FOUND IN Rab-protein geranylgeranyltransferase complex; cytosol (ortholog); INTERACTS WITH acrylamide; ammonium chloride; amphetamine]
LOC108348308	rgd:11504946
Chrm1	rgd:2342	[ENCODES a protein that exhibits G protein-coupled acetylcholine receptor activity; neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN G protein-coupled acetylcholine receptor signaling pathway; neuromuscular synaptic transmission; positive regulation of intracellular protein transport; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; G protein mediated signaling pathway via Galphaq family; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH asthma (ortholog); brain ischemia (ortholog); epilepsy (ortholog); FOUND IN asymmetric synapse; axon terminus; dendrite; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; acetylcholine]
Chrm3	rgd:2343	[ENCODES a protein that exhibits acetylcholine binding; drug binding; G protein-coupled acetylcholine receptor activity; INVOLVED IN G protein-coupled acetylcholine receptor signaling pathway; positive regulation of vascular smooth muscle contraction; regulation of vascular smooth muscle contraction; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; ASSOCIATED WITH Ascites (ortholog); asthma (ortholog); bladder disease (ortholog); FOUND IN asymmetric synapse; axon terminus; dendrite; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4,6-trinitrotoluene]
Chrm4	rgd:2344	[ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity; G protein-coupled acetylcholine receptor activity (ortholog); INVOLVED IN response to organic substance; adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH congestive heart failure; Catatonia (ortholog); Developmental Disabilities (ortholog); FOUND IN asymmetric synapse; axon terminus; cytoplasm; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride]
Chrna3	rgd:2345	[ENCODES a protein that exhibits acetylcholine binding; acetylcholine receptor activity; acetylcholine-gated cation-selective channel activity; INVOLVED IN acetylcholine receptor signaling pathway; heart development; regulation of synaptic vesicle exocytosis; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; nicotine pharmacodynamics pathway; nicotine pharmacokinetics pathway; ASSOCIATED WITH visual epilepsy; alcohol use disorder (ortholog); lung cancer (ortholog); FOUND IN acetylcholine-gated channel complex; cholinergic synapse; dendrite; INTERACTS WITH (S)-anabasine; (S)-nicotine; 3H-1,2-dithiole-3-thione]
LOC103692599	rgd:9261210
Chrna4	rgd:2346	[ENCODES a protein that exhibits acetylcholine binding; acetylcholine-gated cation-selective channel activity; drug binding; INVOLVED IN positive regulation of dopamine secretion; regulation of acetylcholine-gated cation channel activity; synaptic transmission, cholinergic; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; ASSOCIATED WITH congestive heart failure; Alzheimer's disease (ortholog); attention deficit hyperactivity disorder (ortholog); FOUND IN acetylcholine-gated channel complex; cholinergic synapse; dendrite; INTERACTS WITH (S)-anabasine; (S)-nicotine; 17alpha-ethynylestradiol]
LOC108353352	rgd:11479509
Chrna5	rgd:2347	[ENCODES a protein that exhibits acetylcholine binding; acetylcholine-gated cation-selective channel activity; protein-containing complex binding; INVOLVED IN behavioral response to nicotine (ortholog); regulation of synaptic vesicle exocytosis (ortholog); response to nicotine (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH alcohol use disorder (ortholog); anxiety disorder (ortholog); lung cancer (ortholog); FOUND IN acetylcholine-gated channel complex; dendrite; neuronal cell body; INTERACTS WITH 1-naphthyl isothiocyanate; ammonium chloride; bisphenol A]