Terminology Service for NFDI4Health
All terms in RGD
| Label | Id | Description |
|---|---|---|
| Cntf | rgd:2370 | [ENCODES a protein that exhibits ciliary neurotrophic factor receptor binding; cytokine activity; protein-containing complex binding; INVOLVED IN astrocyte activation; membrane hyperpolarization; negative regulation of neuron apoptotic process; PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH behavior/neurological phenotype; ASSOCIATED WITH glaucoma; Huntington's disease; hyperglycemia; FOUND IN axon; cytosol; neuronal cell body; INTERACTS WITH (+)-pilocarpine; 2,6-dinitrotoluene; ammonium chloride] |
| Mcpt4l1 | rgd:1303109 | [predicted to have serine protease activity] |
| Col10a1 | rgd:2371 | [INVOLVED IN cartilage development; endochondral ossification; PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH degenerative disc disease; Osteoarthritis, Hip; body dysmorphic disorder (ortholog); FOUND IN collagen-containing extracellular matrix; cell cortex (ortholog); collagen trimer (ortholog); INTERACTS WITH 3,3',5-triiodo-L-thyronine; 4-phenylbutyric acid; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide] |
| Col11a1 | rgd:2372 | [ENCODES a protein that exhibits heparan sulfate binding; heparin binding; INVOLVED IN ossification; cartilage condensation (ortholog); cartilage development (ortholog); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); angle-closure glaucoma (ortholog); Autosomal Dominant Nonsyndromic Deafness 37 (ortholog); FOUND IN collagen-containing extracellular matrix; collagen trimer (ortholog); collagen type XI trimer (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine] |
| Col11a2 | rgd:2373 | [INVOLVED IN osteoblast differentiation; cartilage development (ortholog); chondrocyte differentiation (ortholog); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; ASSOCIATED WITH autosomal dominant non-syndromic intellectual disability 5 (ortholog); autosomal dominant nonsyndromic deafness 13 (ortholog); autosomal recessive nonsyndromic deafness 53 (ortholog); FOUND IN collagen trimer (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amphetamine] |
| Col12a1 | rgd:2374 | [ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN endodermal cell differentiation (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH Bethlem myopathy (ortholog); Bethlem Myopathy 2 (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); FOUND IN collagen type XII trimer; INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil] |
| Col2a1 | rgd:2375 | [ENCODES a protein that exhibits identical protein binding (ortholog); MHC class II protein binding (ortholog); platelet-derived growth factor binding (ortholog); INVOLVED IN cartilage development; cartilage development involved in endochondral bone morphogenesis; cellular response to insulin-like growth factor stimulus; PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; ASSOCIATED WITH chondrodystrophy; ASSOCIATED WITH Bronchial Fistula; degenerative disc disease; Femur Head Necrosis; FOUND IN collagen-containing extracellular matrix; cytoplasm; basement membrane (ortholog); INTERACTS WITH (R)-carnitine; (R)-mevalonic acid; (R)-pantothenic acid] |
| LOC108349103 | rgd:11504974 | |
| Colq | rgd:2377 | [ENCODES a protein that exhibits heparin binding; INVOLVED IN establishment of protein localization to membrane (ortholog); regulation of synaptic growth at neuromuscular junction (ortholog); skeletal muscle acetylcholine-gated channel clustering (ortholog); ASSOCIATED WITH congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 5 (ortholog); FOUND IN cell junction (ortholog); neuromuscular junction (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil] |
| Cntfr | rgd:1303100 | [ENCODES a protein that exhibits ciliary neurotrophic factor receptor activity; cytokine binding; signaling receptor binding (ortholog); INVOLVED IN brainstem development (ortholog); ciliary neurotrophic factor-mediated signaling pathway (ortholog); negative regulation of neuron apoptotic process (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH distal spinal muscular atrophy 2 (ortholog); Hyperphosphatasia with Mental Retardation Syndrome 2 (ortholog); prostate cancer (ortholog); FOUND IN apical plasma membrane (ortholog); ciliary neurotrophic factor receptor complex (ortholog); CNTFR-CLCF1 complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl] |
| Comp | rgd:2378 | [ENCODES a protein that exhibits extracellular matrix structural constituent; fibronectin binding; vitamin D binding; INVOLVED IN animal organ senescence (ortholog); apoptotic process (ortholog); artery morphogenesis (ortholog); PARTICIPATES IN cell-extracellular matrix signaling pathway; malaria pathway; phagocytosis pathway; ASSOCIATED WITH genetic disease (ortholog); Joint Instability (ortholog); multiple epiphyseal dysplasia (ortholog); FOUND IN collagen-containing extracellular matrix; extracellular space (ortholog); protein-containing complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil] |
| Ly6g5b | rgd:1303101 | [FOUND IN external side of plasma membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; manganese(II) chloride] |
| Comt | rgd:2379 | [ENCODES a protein that exhibits catechol O-methyltransferase activity; INVOLVED IN developmental process; estrogen metabolic process; female pregnancy; PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; ASSOCIATED WITH abnormal dopamine level; ASSOCIATED WITH Brain Injuries; Catalepsy; Chemical and Drug Induced Liver Injury; FOUND IN axon; cell body; cytosol; INTERACTS WITH (-)-epigallocatechin 3-gallate; (3,4-dihydroxyphenyl)acetic acid; (R)-adrenaline] |
| Slpil2 | rgd:1303102 | [ENCODES a protein that exhibits peptidase inhibitor activity (inferred); INVOLVED IN negative regulation of peptidase activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH acrylamide; amphetamine; furan] |
| LOC108348911 | rgd:11455528 | |
| Snu13 | rgd:1303103 | [ENCODES a protein that exhibits ATPase binding (ortholog); box C/D snoRNA binding (ortholog); snoRNA binding (ortholog); INVOLVED IN box C/D snoRNP assembly (ortholog); mRNA splicing, via spliceosome (ortholog); single fertilization (ortholog); PARTICIPATES IN ribosome biogenesis pathway; spliceosome pathway; ASSOCIATED WITH Common Variable Immunodeficiency 4 (ortholog); FOUND IN box C/D snoRNP complex (ortholog); dense fibrillar component (ortholog); nucleolus (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; endosulfan] |
| mt-Tl2 | rgd:1303104 | [predicted to encode tRNA-Leu] |
| LOC108348755 | rgd:11455515 | |
| LOC100909816 | rgd:6501631 | |
| LOC103690261 | rgd:9299846 |