Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Gata2	rgd:2664	[ENCODES a protein that exhibits sequence-specific DNA binding; C2H2 zinc finger domain binding (ortholog); chromatin binding (ortholog); INVOLVED IN cochlea development; neuron migration; positive regulation of cytosolic calcium ion concentration; PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Fungal Lung Diseases; acute myeloid leukemia (ortholog); anemia (ortholog); FOUND IN nucleus; cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amiodarone; ammonium chloride]
Gata4	rgd:2665	[ENCODES a protein that exhibits activating transcription factor binding; cis-regulatory region sequence-specific DNA binding; DNA binding; INVOLVED IN cardiac muscle cell differentiation; cell growth involved in cardiac muscle cell development; cellular response to glucose stimulus; ASSOCIATED WITH congenital heart disease; Diabetes Mellitus, Experimental ; myocardial infarction; FOUND IN nucleus; nuclear body (ortholog); nuclear chromatin (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 1D-myo-inositol 1,4,5-trisphosphate; 2,3,7,8-tetrachlorodibenzodioxine]
LOC108349183	rgd:11397545
Gata6	rgd:2666	[ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding; double-stranded DNA binding; sequence-specific DNA binding; INVOLVED IN negative regulation of pri-miRNA transcription by RNA polymerase II; odontogenesis of dentin-containing tooth; positive regulation of apoptotic process; ASSOCIATED WITH congenital diaphragmatic hernia; pulmonary hypertension; atrial heart septal defect 9 (ortholog); FOUND IN nucleus; nuclear membrane (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol]
LOC108349597	rgd:11397546
Gc	rgd:2667	[ENCODES a protein that exhibits vitamin D binding; actin binding (ortholog); calcidiol binding (ortholog); INVOLVED IN female pregnancy; lactation; response to estradiol; ASSOCIATED WITH brain ischemia; Carotid Artery Injuries; Diabetes Mellitus, Experimental ; FOUND IN axon; cytosol; extracellular space; INTERACTS WITH 1-naphthyl isothiocyanate; 2,6-dinitrotoluene; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile]
Gcg	rgd:2668	[ENCODES a protein that exhibits glucagon receptor binding; hormone activity; identical protein binding (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of appetite; response to L-arginine; PARTICIPATES IN forkhead class A signaling pathway; glucagon signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; Aberrant Crypt Foci (ortholog); Alzheimer's disease (ortholog); FOUND IN extracellular space; cytoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine]
LOC103690800	rgd:9094137
LOC103692690	rgd:9403100
Gck	rgd:2670	[ENCODES a protein that exhibits ADP binding; ATP binding; fructokinase activity; INVOLVED IN carbohydrate phosphorylation; cellular glucose homeostasis; cellular response to glucose starvation; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabolic pathway; glycolysis pathway; ASSOCIATED WITH decreased circulating glucose level; increased circulating free fatty acid level; increased circulating triglyceride level; ASSOCIATED WITH Diabetes Mellitus, Experimental ; fatty liver disease; Insulin Resistance; FOUND IN actin filament; basal cortex; cell cortex; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Gckr	rgd:2671	[ENCODES a protein that exhibits carbohydrate binding; enzyme binding; enzyme inhibitor activity; INVOLVED IN negative regulation of glucokinase activity; negative regulation of hexokinase activity; protein import into nucleus; PARTICIPATES IN glycogen metabolic pathway; ASSOCIATED WITH end stage renal failure (ortholog); Hypertriglyceridemia (ortholog); Metabolic Syndrome (ortholog); FOUND IN cytoplasm; cytosol; mitochondrion; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine]
Gdf11	rgd:2673	[ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN negative regulation of neuron differentiation; animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); FOUND IN extracellular space (ortholog); intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide]
Gdf15	rgd:2674	[ENCODES a protein that exhibits protein homodimerization activity; INVOLVED IN activation of MAPK activity (ortholog); glial cell-derived neurotrophic factor receptor signaling pathway (ortholog); negative regulation of growth hormone receptor signaling pathway (ortholog); ASSOCIATED WITH anemia (ortholog); Cachexia (ortholog); congestive heart failure (ortholog); FOUND IN extracellular region; cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene]
LOC102547357	rgd:7683538
Gdi1	rgd:2676	[ENCODES a protein that exhibits Rab GDP-dissociation inhibitor activity; Rab GTPase binding; INVOLVED IN negative regulation of axonogenesis; positive regulation of axon extension; response to calcium ion; ASSOCIATED WITH adrenoleukodystrophy (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); autistic disorder (ortholog); FOUND IN axon; myelin sheath; neuron projection; INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; ammonium chloride]
Gdnf	rgd:2677	[ENCODES a protein that exhibits glial cell-derived neurotrophic factor receptor binding; growth factor activity; protein homodimerization activity; INVOLVED IN cell population proliferation; cellular response to dexamethasone stimulus; male gonad development; ASSOCIATED WITH Brain Injuries; Optic Nerve Injuries; Parkinsonian Disorders; FOUND IN extracellular space; receptor complex; extracellular region (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-Salsolinol; (S)-AMPA]
Gfap	rgd:2679	[ENCODES a protein that exhibits integrin binding; kinase binding; structural constituent of cytoskeleton; INVOLVED IN positive regulation of glial cell proliferation; regulation of chaperone-mediated autophagy; response to wounding; PARTICIPATES IN chaperone mediated autophagy pathway; ASSOCIATED WITH brain edema; Head Injuries, Closed; Hyperalgesia; FOUND IN astrocyte projection; cytoplasmic side of lysosomal membrane; astrocyte end-foot (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; 1,3,5-trinitro-1,3,5-triazinane]
LOC103695334	rgd:9192589
LOC103695290	rgd:9192585
LOC102550602	rgd:7658581