Terminology Service for NFDI4Health
All terms in RGD
| Label | Id | Description |
|---|---|---|
| C3 | rgd:2232 | [ENCODES a protein that exhibits cofactor binding; lipid binding; C5L2 anaphylatoxin chemotactic receptor binding (ortholog); INVOLVED IN blood coagulation; complement activation; positive regulation of developmental growth; PARTICIPATES IN classical complement pathway; Chagas disease pathway; coagulation cascade pathway; ASSOCIATED WITH Acute Lung Injury; amyotrophic lateral sclerosis; anterior uveitis; FOUND IN extracellular space; cell surface (ortholog); protein-containing complex (ortholog); INTERACTS WITH (S)-colchicine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol] |
| Bace2 | rgd:1303241 | [ENCODES a protein that exhibits aspartic-type endopeptidase activity (ortholog); INVOLVED IN astrocyte activation; glucose homeostasis (ortholog); membrane protein ectodomain proteolysis (ortholog); PARTICIPATES IN Alzheimer's disease pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); autistic disorder (ortholog); frontotemporal dementia (ortholog); FOUND IN cytoplasm; dense core granule; Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A] |
| Klk10 | rgd:1303242 | [ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); ductal carcinoma in situ (ortholog); ovarian cancer (ortholog); INTERACTS WITH bisphenol A; decabromodiphenyl ether; sodium dichromate] |
| Sptb | rgd:1303243 | [ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); ankyrin binding (ortholog); INVOLVED IN hemopoiesis (ortholog); plasma membrane organization (ortholog); porphyrin-containing compound biosynthetic process (ortholog); ASSOCIATED WITH congenital hemolytic anemia (ortholog); Elliptocytosis 3 (ortholog); hemolytic anemia (ortholog); FOUND IN cell surface (ortholog); cortical cytoskeleton (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; acrylamide; bisphenol A] |
| C4bpa | rgd:2235 | [ENCODES a protein that exhibits complement binding (inferred); INVOLVED IN binding of sperm to zona pellucida (ortholog); negative regulation of complement activation, classical pathway (ortholog); positive regulation of protein catabolic process (ortholog); PARTICIPATES IN coagulation cascade pathway; complement system pathway; ASSOCIATED WITH autistic disorder (ortholog); Radiation Pneumonitis (ortholog); FOUND IN acrosomal matrix (ortholog); acrosomal vesicle (ortholog); cell body (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene] |
| Kprp | rgd:1303244 | [ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH acrylamide; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)] |
| C4bpb | rgd:2236 | [INVOLVED IN negative regulation of complement activation, classical pathway (ortholog); positive regulation of protein catabolic process (ortholog); regulation of opsonization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; coagulation cascade pathway; complement system pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione] |
| Rtn2 | rgd:1303245 | [INVOLVED IN intracellular protein transmembrane transport (ortholog); regulation of glucose import (ortholog); ASSOCIATED WITH hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 10 (ortholog); hereditary spastic paraplegia 12 (ortholog); FOUND IN endoplasmic reticulum (ortholog); T-tubule (ortholog); terminal cisterna (ortholog); INTERACTS WITH all-trans-retinoic acid; bisphenol A; cadmium dichloride] |
| C5 | rgd:2237 | [ENCODES a protein that exhibits C5a anaphylatoxin chemotactic receptor binding; INVOLVED IN cellular calcium ion homeostasis; chemotaxis; glucose homeostasis; PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; ASSOCIATED WITH adult respiratory distress syndrome; asthma; brain edema; FOUND IN extracellular space; membrane attack complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine] |
| Dek | rgd:1303246 | [ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN cell quiescence (ortholog); regulation of double-strand break repair (ortholog); regulation of double-strand break repair via nonhomologous end joining (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Breast Neoplasms (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN contractile fiber (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; bisphenol A] |
| C6 | rgd:2238 | [INVOLVED IN positive regulation of apoptotic process; in utero embryonic development (ortholog); positive regulation of activation of membrane attack complex (ortholog); PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; ASSOCIATED WITH decreased susceptibility to experimental autoimmune myasthenia gravis; ASSOCIATED WITH Alcoholic Liver Diseases; end stage renal failure; Experimental Autoimmune Encephalomyelitis; FOUND IN extracellular space; membrane attack complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene] |
| Slc25a47 | rgd:1303247 | [INVOLVED IN acyl carnitine transmembrane transport (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); prostate cancer (ortholog); FOUND IN integral component of membrane (inferred); mitochondrial inner membrane (inferred); INTERACTS WITH 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran] |
| C8b | rgd:2239 | [ENCODES a protein that exhibits protein-containing complex binding; INVOLVED IN complement activation, alternative pathway (inferred); complement activation, classical pathway (inferred); cytolysis (inferred); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Entamoebiasis pathway; ASSOCIATED WITH myocardial infarction; complement component 6 deficiency (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN extracellular region; extracellular space; membrane attack complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole] |
| AABR07052387.1 | rgd:15013838 | |
| U6 | rgd:15013839 | |
| AABR07033324.1 | rgd:15013832 | [INVOLVED IN clathrin coat disassembly (inferred)] |
| AABR07061279.1 | rgd:15013833 | |
| Gm25492 | rgd:15013830 | |
| AABR07050056.1 | rgd:15013831 | |
| U2 | rgd:15013836 |