Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Mir341	rgd:9685630	[microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]]
LOC103691644	rgd:9445967
LOC103691270	rgd:9445960
Mir297	rgd:9685629	[INVOLVED IN negative regulation of thyroid gland epithelial cell proliferation]
Mir466c	rgd:9685628	[INTERACTS WITH paracetamol]
LOC100365995	rgd:2317994
LOC103693082	rgd:9445976
LOC103692585	rgd:9445972
LOC103694805	rgd:9396464
Cxcr6	rgd:1642118	[ENCODES a protein that exhibits C-X-C chemokine binding (ortholog); C-X-C chemokine receptor activity (ortholog); INVOLVED IN chemokine-mediated signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); inflammatory response (inferred); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH systemic scleroderma (ortholog); FOUND IN cell (inferred); integral component of membrane (inferred); INTERACTS WITH bisphenol A; furan; 1-chloro-2,4-dinitrobenzene (ortholog)]
LOC102555308	rgd:7726144
Plekhh3	rgd:1304854	[INVOLVED IN signal transduction (inferred); FOUND IN cytoskeleton (inferred); INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; dibutyl phthalate]
Capn7	rgd:1304855	[ENCODES a protein that exhibits endopeptidase activity (ortholog); MIT domain binding (ortholog); INVOLVED IN positive regulation of epithelial cell migration (ortholog); proteolysis (ortholog); self proteolysis (ortholog); INTERACTS WITH bisphenol A; gentamycin; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)]
Slf1	rgd:1304857	[ENCODES a protein that exhibits protein-containing complex binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); positive regulation of double-strand break repair (ortholog); positive regulation of maintenance of mitotic sister chromatid cohesion (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nuclear inclusion body (ortholog); INTERACTS WITH bisphenol A; trichloroethene; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)]
Vps39	rgd:1304858	[INVOLVED IN autophagy (ortholog); endosomal vesicle fusion (ortholog); endosome to lysosome transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); schizophrenia (ortholog); FOUND IN AP-3 adaptor complex (ortholog); HOPS complex (ortholog); late endosome membrane (ortholog); INTERACTS WITH bisphenol A; quercetin; vinclozolin]
Sh3glb1	rgd:1304859	[ENCODES a protein that exhibits fatty acid binding (ortholog); identical protein binding (ortholog); lysophosphatidic acid acyltransferase activity (ortholog); INVOLVED IN positive regulation of dendrite extension; positive regulation of dendrite morphogenesis; positive regulation of neurotrophin TRK receptor signaling pathway; PARTICIPATES IN mitochondria fission pathway; endocytosis pathway; FOUND IN early endosome; membrane; neuron projection; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; diazinon]
Smarcc1	rgd:1304850	[ENCODES a protein that exhibits chromatin binding (ortholog); protein N-terminus binding (ortholog); INVOLVED IN prostate gland development; animal organ morphogenesis (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); intracellular (ortholog); nBAF complex (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide]
Cdk10	rgd:1304851	[ENCODES a protein that exhibits cyclin-dependent protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN negative regulation of cilium assembly (ortholog); peptidyl-threonine phosphorylation (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH Al Kaissi Syndrome (ortholog); FOUND IN ciliary basal body (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; cobalt dichloride]
Defa24	rgd:1304852
Dlx2	rgd:1304853	[ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN branching morphogenesis of a nerve (ortholog); cartilage development (ortholog); cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; C60 fullerene]