Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Zfp598	rgd:1304900	[ENCODES a protein that exhibits ribosome binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN protein monoubiquitination (ortholog); protein ubiquitination (ortholog); rescue of stalled ribosome (ortholog); ASSOCIATED WITH tuberous sclerosis 2 (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A]
Nlrc3	rgd:1304902	[ENCODES a protein that exhibits phosphatidylinositol 3-kinase regulatory subunit binding (ortholog); INVOLVED IN I-kappaB kinase/NF-kappaB signaling (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of epithelial cell proliferation (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN centriolar satellite (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH amphetamine; 1,1-dichloroethene (ortholog); aflatoxin B2 (ortholog)]
LOC102553985	rgd:7559320
Gpat2	rgd:1304904	[ENCODES a protein that exhibits glycerol-3-phosphate O-acyltransferase activity (ortholog); INVOLVED IN glycerol-3-phosphate metabolic process (ortholog); piRNA biosynthetic process (ortholog); triglyceride biosynthetic process (ortholog); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; FOUND IN mitochondrion (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil]
Hist1h2ao	rgd:1304905	[ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cell differentiation (inferred); DNA-templated transcription, initiation (inferred); multicellular organism development (inferred); PARTICIPATES IN systemic lupus erythematosus pathway; FOUND IN nucleoplasm (inferred); nucleosome (inferred)]
Syt8	rgd:68399	[ENCODES a protein that exhibits clathrin binding; calcium-dependent protein binding (ortholog); INVOLVED IN acrosome reaction (ortholog); FOUND IN cytoplasm (ortholog); vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A]
Pde7a	rgd:68391	[ENCODES a protein that exhibits cyclic-nucleotide phosphodiesterase activity; 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); INVOLVED IN cAMP-mediated signaling; PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH acrylamide; ammonium chloride; bisphenol A]
Alas1	rgd:68392	[ENCODES a protein that exhibits 5-aminolevulinate synthase activity; identical protein binding (ortholog); INVOLVED IN cellular response to insulin stimulus; cellular response to organic cyclic compound; response to cAMP; PARTICIPATES IN heme biosynthetic pathway; acute intermittent porphyria pathway; dihydropyrimidine dehydrogenase deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; porphyria; pulmonary hypertension; FOUND IN mitochondrion; cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; 1,2,4-trichlorobenzene]
Kcnd2	rgd:68393	[ENCODES a protein that exhibits A-type (transient outward) potassium channel activity; ion channel activity; potassium channel activity; INVOLVED IN action potential; cardiac muscle cell action potential; cellular response to drug; PARTICIPATES IN excitatory synaptic transmission pathway; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; ASSOCIATED WITH early myoclonic encephalopathy (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN caveola; dendrite; dendritic spine; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Kcnd3	rgd:68394	[ENCODES a protein that exhibits A-type (transient outward) potassium channel activity; ion channel activity; potassium channel activity; INVOLVED IN cellular response to BMP stimulus; potassium ion export across plasma membrane; potassium ion import across plasma membrane; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Brugada syndrome (ortholog); Brugada syndrome 9 (ortholog); FOUND IN caveola; dendrite; integral component of plasma membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Hsf2	rgd:68395	[ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allethrin; ammonium chloride]
Inppl1	rgd:68396	[ENCODES a protein that exhibits inositol-polyphosphate 5-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate binding; SH2 domain binding (ortholog); INVOLVED IN brain development; inositol trisphosphate metabolic process; negative regulation of DNA replication; PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Insulin Resistance; Experimental Liver Cirrhosis (ortholog); hypertension (ortholog); FOUND IN lamellipodium; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A]
Syt4	rgd:68397	[ENCODES a protein that exhibits clathrin binding; phosphatidylserine binding; protein heterodimerization activity; INVOLVED IN brain development; dense core granule cytoskeletal transport; negative regulation of calcium ion-dependent exocytosis; ASSOCIATED WITH visual epilepsy; melanoma (ortholog); FOUND IN astrocyte projection; axon; dense core granule; INTERACTS WITH ammonium chloride; bisphenol A; clozapine]
Kcnh1	rgd:68398	[ENCODES a protein that exhibits 14-3-3 protein binding; calmodulin binding; delayed rectifier potassium channel activity; INVOLVED IN cellular response to calcium ion; ion transmembrane transport; potassium ion transmembrane transport; ASSOCIATED WITH Breast Neoplasms (ortholog); colorectal adenocarcinoma (ortholog); epilepsy (ortholog); FOUND IN axolemma; axon; cell surface; INTERACTS WITH ammonium chloride; atrazine; bisphenol A]
LOC103690440	rgd:9215769
Rad52	rgd:1304975	[ENCODES a protein that exhibits DNA binding (ortholog); identical protein binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); cellular response to oxidative stress (ortholog); DNA double-strand break processing involved in repair via single-strand annealing (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH hereditary sensory and autonomic neuropathy type 2 (ortholog); hyperphosphatemic familial tumoral calcinosis (ortholog); Lung Neoplasms (ortholog); FOUND IN nucleus (ortholog); protein-containing complex (ortholog); protein-DNA complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; dibutyl phthalate]
Odf3l1	rgd:1304976	[ASSOCIATED WITH chromosome 15q24 deletion syndrome (ortholog); schizophrenia (ortholog); INTERACTS WITH bisphenol A; (-)-demecolcine (ortholog); aflatoxin B1 (ortholog)]
Nup214	rgd:1304977	[ENCODES a protein that exhibits nuclear localization sequence binding; nuclear export signal receptor activity (ortholog); structural constituent of nuclear pore (ortholog); INVOLVED IN mitotic cell cycle; mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mRNA nuclear export pathway; NXF1-NXT1 export pathway; ASSOCIATED WITH acute lymphocytic leukemia (ortholog); acute myeloid leukemia (ortholog); Developmental Disabilities (ortholog); FOUND IN nuclear envelope; cytoplasmic side of nuclear pore (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; valproic acid]
Mettl15	rgd:1304978	[INTERACTS WITH bisphenol A; chlorpyrifos; tetrachloromethane]
Usp8	rgd:1304979	[ENCODES a protein that exhibits thiol-dependent ubiquitin-specific protease activity (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; cellular response to nerve growth factor stimulus; regulation of protein catabolic process at postsynapse, modulating synaptic transmission; PARTICIPATES IN mitochondrial autophagy pathway; endocytosis pathway; ASSOCIATED WITH ACTH-secreting pituitary adenoma (ortholog); hereditary spastic paraplegia (ortholog); pituitary-dependent Cushing's disease (ortholog); FOUND IN cytosol; dendritic spine; early endosome; INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrobenzenesulfonic acid; bisphenol A]