Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Rnf34	rgd:628636	[ENCODES a protein that exhibits ubiquitin protein ligase activity; ubiquitin-protein transferase activity; p53 binding (ortholog); INVOLVED IN cellular response to cold (ortholog); negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A]
LOC100359474	rgd:2323819
Pycard	rgd:628637	[ENCODES a protein that exhibits ion channel binding; protease binding; BMP receptor binding (ortholog); INVOLVED IN positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; activation of cysteine-type endopeptidase activity (ortholog); activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; influenza A pathway; NOD-like receptor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Albuminuria (ortholog); branched-chain keto acid dehydrogenase kinase deficiency (ortholog); FOUND IN neuronal cell body; protein-containing complex; AIM2 inflammasome complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol]
LOC103691515	rgd:9271705
Cylc1	rgd:2323810	[ENCODES a protein that exhibits structural constituent of cytoskeleton (inferred); INVOLVED IN cytoskeleton organization (inferred); ASSOCIATED WITH autistic disorder (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN acrosomal matrix (ortholog); INTERACTS WITH aflatoxin B1 (ortholog); cadmium dichloride (ortholog); formaldehyde (ortholog)]
LOC102549566	rgd:7673172
Gzma	rgd:628640	[ENCODES a protein that exhibits protein homodimerization activity (ortholog); serine-type endopeptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN negative regulation of DNA binding (ortholog); negative regulation of endodeoxyribonuclease activity (ortholog); negative regulation of oxidoreductase activity (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); Experimental Liver Cirrhosis (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol]
Atg10	rgd:1587624	[ENCODES a protein that exhibits Atg12 conjugating enzyme activity (ortholog); Atg12 transferase activity (ortholog); INVOLVED IN autophagy (ortholog); ER overload response (ortholog); positive regulation of protein modification process (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN intracellular (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide]
Uba6	rgd:1308324	[ENCODES a protein that exhibits FAT10 activating enzyme activity (ortholog); ubiquitin activating enzyme activity (ortholog); INVOLVED IN amygdala development (ortholog); dendritic spine development (ortholog); hippocampus development (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; diazinon]
RGD1563636	rgd:1563636	[INTERACTS WITH bisphenol A; indole-3-methanol; testosterone]
LOC688553	rgd:1587626	[ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); INTERACTS WITH bisphenol A; cisplatin (ortholog); copper atom (ortholog)]
Edem1	rgd:1563633	[ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN mannose trimming involved in glycoprotein ERAD pathway (ortholog); positive regulation of retrograde protein transport, ER to cytosol (ortholog); trimming of terminal mannose on C branch (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN aggresome (ortholog); endoplasmic reticulum (ortholog); integral component of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; bisphenol A]
Myf5	rgd:1308322	[ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN camera-type eye development (ortholog); cartilage condensation (ortholog); embryonic skeletal system morphogenesis (ortholog); ASSOCIATED WITH chronic progressive external ophthalmoplegia (ortholog); ophthalmoplegia (ortholog); scoliosis (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH bisphenol A; bupivacaine; chromium atom]
Cactin	rgd:1563634	[INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to tumor necrosis factor (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytosol (ortholog); nuclear speck (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan]
Uba7	rgd:1308323	[ENCODES a protein that exhibits ISG15 activating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular protein modification process (ortholog); ISG15-protein conjugation (ortholog); modification-dependent protein catabolic process (ortholog); PARTICIPATES IN Parkinson's disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH squamous cell carcinoma (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene]
Znrf4	rgd:1563631	[INVOLVED IN ubiquitin-dependent protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; lead nitrate]
LOC103690749	rgd:9222780
Wwc1	rgd:1308329	[ENCODES a protein that exhibits protein binding, bridging; kinase binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cell migration; negative regulation of hippo signaling (ortholog); negative regulation of organ growth (ortholog); ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN protein-containing complex; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; cobalt dichloride]
LOC688557	rgd:1587622
Dennd10	rgd:1308326	[ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN endosome transport via multivesicular body sorting pathway (ortholog); protein transport (ortholog); regulation of early endosome to late endosome transport (ortholog); FOUND IN cell (ortholog); late endosome (ortholog); INTERACTS WITH bisphenol A; clozapine; flutamide]