Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Transmembrane protein 234	Q8R1E7
Zinc finger protein 703	P0CL69	[Function: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.]
Zinc finger and SCAN domain-containing protein 21	Q07231	[Function: Strong transcriptional activator. Associated with meiosis in both male and female gametogenesis. May have different functions in somatic cells.]
Zinc finger and SCAN domain-containing protein 2	Q07230	[Function: May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.]
Protein PTHB1	Q811G0	[Function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization (By similarity).]
DAP3-binding cell death enhancer 1	Q9DCV6	[Function: Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.]
Putative tripartite motif-containing protein 75	A6NK02
Keratin, type II cytoskeletal 7	Q9DCV7	[Function: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.]
Zinc finger protein 239	P24399	[Function: May be involved in transcriptional regulation.]
Regulator of microtubule dynamics protein 1	Q9DCV4
Cis-aconitate decarboxylase	A6NK06	[Function: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.]
Diacylglycerol O-acyltransferase 2	Q9DCV3	[Function: Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT) (By similarity).]
Protein Niban 2	Q8R1F1	[Function: May play a role in apoptosis suppression.]
Peroxisome biogenesis factor 2	P24392	[Function: Somewhat implicated in the biogenesis of peroxisomes.]
ER lumen protein-retaining receptor 1	P24390	[Function: Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.]
Leydig cell tumor 10 kDa protein homolog	Q8R1F0	[Function: May have a potential role in hypercalcemia of malignancy.]
Putative hydroxypyruvate isomerase	Q8R1F5	[Function: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).]
Protein HID1	Q8R1F6
Interleukin-4 receptor subunit alpha	P24394	[Function: Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.]
Gastrin-releasing peptide	P24393	[Function: Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity). Contributes to the regulation of food intake (PubMed:17208656).]