Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Ubiquitin conjugation factor E4 A	Q6P7A2	[Function: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.]
Hepatocyte cell adhesion molecule	Q14CZ8	[Function: Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.]
Ankyrin repeat domain-containing protein 45	Q810N6
Uncharacterized protein C12orf60 homolog	Q810N5
FAST kinase domain-containing protein 3, mitochondrial	Q14CZ7	[Function: Required for normal mitochondrial respiration (PubMed:20869947). Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713).]
Coiled-coil domain-containing protein 172	Q810N9
LEM domain-containing protein 2	Q6DVA0	[Function: Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT (PubMed:25790465). Required for myoblast differentiation involving regulation of ERK signaling (PubMed:17062158, PubMed:19720741).]
Signal-transducing adaptor protein 2	Q8R0L1	[Function: Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.]
DNA ligase 3	P97386	[Function: The alpha isoform interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. The beta isoform does not interact with XRCC1 and may be specifically involved in the completion of homologous recombination events that occur during meiotic prophase.]
Ubiquitin carboxyl-terminal hydrolase 17-like protein 21	D6R901	[Function: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.]
Annexin A11	P97384	[Function: Required for midbody formation and completion of the terminal phase of cytokinesis (By similarity). Binds specifically to calcyclin in a calcium-dependent manner.]
Voltage-gated potassium channel subunit beta-3	P97382	[Function: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv2.2 but not Kv2.1.]
Monocarboxylate transporter 5	Q8R0M8	[Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).]
Transmembrane protein KIAA1109	Q2LD37
Transport and Golgi organization protein 2 homolog	Q6ICL3
Palmitoyltransferase ZDHHC20	Q5W0Z9	[Function: Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245).]
Solute carrier family 35 member E4	Q6ICL7	[Function: Putative transporter.]
Putative methyl-CpG-binding domain protein 3-like 5	A6NJ08
Superoxide dismutase [Cu-Zn]	P00441	[Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.]
28S ribosomal protein S11, mitochondrial	Q9DCA2