Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Protein tyrosine phosphatase type IVA 1	Q93096	[Function: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.]
Homogentisate 1,2-dioxygenase	Q93099
Acetyl-coenzyme A thioesterase	Q9DBK0	[Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A thioesterase 12/ACOT12 preferentially hydrolyzes acetyl-CoA.]
Protein Wnt-2b	Q93097	[Function: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.]
Protein Wnt-8b	Q93098	[Function: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.]
Guanylate cyclase 2D	P51839	[Function: Functions as an olfactory receptor activated by a urine odorant, uroguanylin (PubMed:18178149). Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand (PubMed:18178149). Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity).]
Keratin, type II cytoskeletal 5	Q6P6Q2
AT-rich interactive domain-containing protein 3C	A6NKF2
SAC3 domain-containing protein 1	A6NKF1	[Function: Involved in centrosome duplication and mitotic progression.]
Protein FAM171B	Q14CH0
Molybdenum cofactor sulfurase	Q14CH1	[Function: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.]
Alanine--tRNA ligase, mitochondrial	Q14CH7	[Function: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.]
Rho guanine nucleotide exchange factor 25	Q6P720	[Function: May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).]
Inhibitor of nuclear factor kappa-B kinase-interacting protein	Q70UQ0	[Function: Target of p53/TP53 with pro-apoptotic function.]
Membrane magnesium transporter 2	Q6P719	[Function: Mediates Mg(2+) transport.]
von Willebrand factor A domain-containing protein 5B1	Q5TIE3
Nucleosome assembly protein 1-like 2	P51860	[Function: Acidic protein which may be involved in interactions with other proteins or DNA.]
Protein mono-ADP-ribosyltransferase PARP6	Q6P6P7	[Function: Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.]
Bifunctional coenzyme A synthase	Q9DBL7	[Function: Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.]
Teratocarcinoma-derived growth factor	P51865	[Function: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated Tdgf1 acts as a Nodal coreceptor in cis. Shedding of Tdgf1 by Tmem8a modulates Nodal signaling by allowing soluble Tdgf1 to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.]