Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Ig kappa chain V-VI region XRPC 24	P01676
Ig kappa chain V-III region PC 2485/PC 4039	P01673
PHD finger protein 6	Q8IWS0	[Function: Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.]
Ig kappa chain V-III region PC 2154	P01674
Choline kinase alpha	O54804	[Function: Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline (By similarity).]
Ig kappa chain V-III region PC 7175	P01671
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	O15239	[Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.]
P2X purinoceptor 6	O54803	[Function: Receptor for ATP that acts as a ligand-gated ion channel.]
Ig kappa chain V-III region PC 7940	P01672
Uncharacterized protein C19orf18	Q8NEA5
F-box only protein 36	Q8NEA4	[Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.]
Laminin subunit alpha-5	O15230	[Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.]
Zinc finger protein GLIS3	Q8NEA6	[Function: Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).]
Matrilin-3	O15232	[Function: Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.]
ER degradation-enhancing alpha-mannosidase-like protein 3	Q2HXL6	[Function: Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity.]
Germ cell-less protein-like 2	Q8NEA9	[Function: Possible function in spermatogenesis. Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312).]
Zinc finger protein 185	O15231	[Function: May be involved in the regulation of cellular proliferation and/or differentiation.]
NUT family member 2E	B1AL46
Transmembrane protein 44	Q2T9K0
Volume-regulated anion channel subunit LRRC8A	Q8IWT6	[Function: Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24725410, PubMed:24790029, PubMed:26530471, PubMed:26824658, PubMed:28193731, PubMed:29769723). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine (PubMed:24725410, PubMed:24790029, PubMed:26530471, PubMed:26824658, PubMed:28193731). Mediates efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress (PubMed:28193731). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin (PubMed:26530471). Required for in vivo channel activity, together with at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731). Can form functional channels by itself (in vitro) (PubMed:26824658). Involved in B-cell development: required for the pro-B cell to pre-B cell transition (PubMed:14660746). Also required for T-cell development (By similarity). May play a role in lysosome homeostasis (PubMed:31270356).]