Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
GA-binding protein subunit beta-1	Q00420	[Function: Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:25200183). Acts as a a master regulator of nuclear-encoded mitochondrial genes (PubMed:25200183).]
NACHT, LRR and PYD domains-containing protein 7	Q8WX94	[Function: Inhibits CASP1/caspase-1-dependent IL1B secretion.]
Calcipressin-3	Q9JKK0	[Function: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).]
A-kinase anchor protein 9	Q99996	[Function: Associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations.]
Host cell factor C1 regulator 1	Q9NWW0	[Function: Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.]
Ankyrin repeat and SOCS box protein 5	Q8WWX0	[Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity).]
Transcription cofactor vestigial-like protein 1	Q99990	[Function: May act as a specific coactivator for the mammalian TEFs.]
GA-binding protein alpha chain	Q00422	[Function: Transcription factor capable of interacting with purine rich repeats (GA repeats).]
Palladin	Q8WX93	[Function: Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci.]
Olfactory receptor 2V2	Q96R30	[Function: Odorant receptor.]
Secretoglobin family 3A member 1	Q96QR1	[Function: Secreted cytokine-like protein. Inhibits cell growth in vitro.]
Negative elongation factor B	Q8WX92	[Function: (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II (PubMed:23884411). In vitro, binds weakly to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1 (PubMed:23884411).]
GTPase IMAP family member 6	Q8K349
Activin receptor type-1C	Q8K348	[Function: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.]
Galactosylceramide sulfotransferase	Q99999	[Function: Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro).]
Selenoprotein M	Q8WWX9	[Function: May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.]
Sodium/myo-inositol cotransporter 2	Q8WWX8	[Function: Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.]
Transcriptional activator protein Pur-beta	Q96QR8	[Function: Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).]
Carbonyl reductase [NADPH] 3	Q8K354	[Function: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).]
Ubiquinol-cytochrome-c reductase complex assembly factor 3	Q8K2T4	[Function: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.]