Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| Actin-related protein T3 | Q9BYD9 | |
| 39S ribosomal protein L9, mitochondrial | Q9BYD2 | |
| 39S ribosomal protein L4, mitochondrial | Q9BYD3 | |
| 39S ribosomal protein L13, mitochondrial | Q9BYD1 | |
| Spermatid-associated protein | Q32MG2 | |
| cAMP-responsive element modulator | P27699 | [Function: Plays a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.] |
| Signal peptidase complex catalytic subunit SEC11C | Q9BY50 | [Function: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.] |
| Gasdermin-A2 | Q32M21 | [Function: May promote pyroptosis. Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity. The physiological relevance of these observations is unknown.] |
| Tudor domain-containing protein 1 | Q9BXT4 | [Function: Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).] |
| Voltage-dependent calcium channel gamma-6 subunit | Q9BXT2 | [Function: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.] |
| Putative SNURF-like protein | B1AK76 | |
| Protein broad-minded | Q3URV1 | [Function: Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.] |
| Nucleolar and spindle-associated protein 1 | Q9BXS6 | [Function: Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.] |
| Transmembrane protein 59 | Q9BXS4 | [Function: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).] |
| Eukaryotic translation initiation factor 2A | Q9BY44 | [Function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.] |
| AP-1 complex subunit mu-1 | Q9BXS5 | [Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.] |
| Peroxisomal trans-2-enoyl-CoA reductase | Q9BY49 | [Function: Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.] |
| Solute carrier family 26 member 6 | Q9BXS9 | [Function: Apical membrane chloride-bicarbonate exchanger. Its association with carbonic anhydrase CA2 forms a bicarbonate transport metabolon; hence maximizes the local concentration of bicarbonate at the transporter site.] |
| Complement C1q subcomponent subunit A | P98086 | [Function: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.] |
| Testis-expressed protein 12 | Q9BXU0 |