Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Transmembrane and coiled-coil domain-containing protein 4	Q499U8
Non-structural maintenance of chromosomes element 1 homolog	Q499U6	[Function: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. Involved in maintenance of genome integrity, DNA damage response and DNA repair. NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair.]
Dynein regulatory complex subunit 4	Q499U4	[Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker. Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner.]
Engulfment and cell motility protein 3	Q499U2	[Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).]
Mitochondrial glycine transporter	Q499U1	[Function: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.]
DnaJ homolog subfamily C member 5B	D3ZD82
Ras-related protein Rab-34, isoform NARR	P0DI83
Voltage-dependent calcium channel gamma-2 subunit	Q71RJ2	[Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.]
Trafficking protein particle complex subunit 2B	P0DI82	[Function: Prevents transcriptional repression and induction of cell death by ENO1. May play a role in vesicular transport from endoplasmic reticulum to Golgi.]
Transcription elongation factor A N-terminal and central domain-containing protein	Q3US16
Zinc finger protein 48	Q3US17	[Function: May be involved in transcriptional regulation.]
Specifically androgen-regulated gene protein	Q499V8	[Function: Putative androgen-specific receptor.]
Zinc finger CCHC-type and RNA-binding motif-containing protein 1	Q499V6
Cell cycle checkpoint control protein RAD9B	Q499V3
DNA replication complex GINS protein SLD5	Q499W2	[Function: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. SLD5 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity).]
Testis-expressed protein 10	Q3URQ0	[Function: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity).]
Asparagine synthetase [glutamine-hydrolyzing]	P49088
Putative uncharacterized protein LOC152225	Q0VG73
Bcl-2-like protein 13	Q9BXK5	[Function: May promote the activation of caspase-3 and apoptosis.]
Krueppel-like factor 16	Q9BXK1	[Function: Transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. Modulates dopaminergic transmission in the brain (By similarity).]