Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
TM2 domain-containing protein 1	Q9BX74	[Function: May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.]
Melanoma-derived growth regulatory protein	Q62946	[Function: May function during cartilage development and maintenance.]
SAP domain-containing ribonucleoprotein	Q498U4	[Function: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity).]
Solute carrier family 25 member 40	Q498U3
Kinesin-like protein KIF22	Q3V300	[Function: Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells.]
TANK-binding kinase 1-binding protein 1	A2A9T0	[Function: Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus.]
Arylsulfatase I	Q32KJ8	[Function: Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts.]
Arylsulfatase G	Q32KJ9	[Function: Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate.]
N-acetylgalactosamine-6-sulfatase	Q32KJ6
Zinc finger E-box-binding homeobox 1	Q62947	[Function: Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs (By similarity).]
Caspase recruitment domain-containing protein 6	Q9BX69	[Function: May be involved in apoptosis.]
DOMON domain-containing protein FRRS1L	D3ZE85	[Function: Important modulator of glutamate signaling pathway.]
Arylsulfatase K	Q32KJ2
Cortistatin	Q62949	[Function: Neuropeptide with neuronal depressant and sleep-modulating properties.]
Junctional adhesion molecule C	Q9BX67	[Function: Promotes chemotaxis of vascular endothelial cells and stimulates angiogenesis.]
Histidine triad nucleotide-binding protein 2, mitochondrial	Q9BX68	[Function: Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.]
Single-stranded DNA-binding protein 3	Q9BWW4	[Function: May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.]
Transient receptor potential cation channel subfamily M member 6	Q9BX84	[Function: Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.]
Complement component C9	Q62930	[Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.]
Golgi SNAP receptor complex member 1	Q62931	[Function: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.]