Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| ARL14 effector protein-like | P0DKL9 | |
| PDZ and LIM domain protein 3 | Q66HS7 | [Function: May play a role in the organization of actin filament arrays within muscle cells.] |
| Transmembrane protein 62 | Q0P6H9 | |
| Short-wave-sensitive opsin 1 | P03999 | [Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (Probable). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity). Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity). May increase spectral sensitivity in dim light (By similarity).] |
| Agrin | P25304 | [Function: this released fragment is important for agrin signaling and to exert a maximal dendritic filopodia-inducing effect. All 'z' splice variants (z+) of this fragment also show an increase in the number of filopodia.] |
| Gap junction beta-3 protein | P25305 | [Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.] |
| BRD4-interacting chromatin-remodeling complex-associated protein-like | Q6AI39 | [Function: Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.] |
| Glial fibrillary acidic protein | P03995 | [Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.] |
| Hyaluronan and proteoglycan link protein 1 | P03994 | [Function: Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.] |
| Gastrin | P01350 | [Function: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.] |
| ATPase family protein 2 homolog | Q8NB90 | [Function: ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes. May be involved in morphological and functional mitochondrial transformations during spermatogenesis.] |
| Keratinocyte differentiation factor 1 | Q8NAX2 | [Function: Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).] |
| Fanconi anemia group B protein | Q8NB91 | [Function: DNA repair protein required for FANCD2 ubiquitination.] |
| Ras association domain-containing protein 4 | Q8CB96 | [Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.] |
| Proton channel OTOP1 | Q7RTM1 | [Function: Proton-selective channel that specifically transports protons into cells (PubMed:29371428). Proton channel activity is only weakly-sensitive to voltage (By similarity). Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes (PubMed:29371428). In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration (By similarity). Probably acts by maintaining the pH appropriate for formation of otoconia (By similarity). Regulates purinergic control of intracellular calcium in vestibular supporting cells (By similarity). May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol (By similarity). Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction (By similarity).] |
| Class I histocompatibility antigen, Non-RT1.A alpha-1 chain | P15978 | [Function: Involved in the presentation of foreign antigens to the immune system.] |
| Inactive ubiquitin carboxyl-terminal hydrolase 53 | P15975 | [Function: Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions (PubMed:26609154). Has no peptidase activity (PubMed:26609154).] |
| Erythroid transcription factor | P15976 | [Function: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781).] |
| Putative per-hexamer repeat protein 1 | P15973 | |
| Putative per-hexamer repeat protein 4 | P15974 |