Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Paraneoplastic antigen Ma1	Q8ND90
Protein lin-52 homolog	Q8CD94
LRRN4 C-terminal-like protein	Q8ND94
Keratin-like protein KRT222	Q8CCX5
SPARC-related modular calcium-binding protein 2	Q8CD91	[Function: Can stimulate endothelial cell proliferation, migration, as well as angiogenesis (By similarity). Promotes matrix assembly and cell adhesiveness.]
Tetratricopeptide repeat protein 27	Q8CD92
WASP homolog-associated protein with actin, membranes and microtubules	Q571B6	[Function: Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Proposed to use coordinated actin-nucleating and microtubule-binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex. Required for RhoD-dependent actin reorganization such as in cell adhesion and cell migration (By similarity). Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.]
Prolyl 3-hydroxylase 3	Q8IVL6	[Function: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.]
Prolyl 3-hydroxylase 2	Q8IVL5	[Function: Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (PubMed:18487197). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity). Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1 (PubMed:18487197). Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline (PubMed:18487197). Has no activity on substrates that lack 4-hydroxyproline in the third position (PubMed:18487197).]
Neuron navigator 2	Q8IVL1	[Function: Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.]
Neuron navigator 3	Q8IVL0	[Function: May regulate IL2 production by T-cells. May be involved in neuron regeneration.]
Lymphocyte expansion molecule	Q3ZCV2
Zinc finger X-linked protein ZXDB	A2CE44	[Function: Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.]
Protein fosB	P13346	[Function: FosB interacts with Jun proteins enhancing their DNA binding activity.]
Myogenic factor 5	P13349	[Function: Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:29887215). Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.]
Myb/SANT-like DNA-binding domain-containing protein 4	Q8NCY6
Carboxypeptidase O	Q8IVL8	[Function: Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues.]
Putative uncharacterized protein encoded by LINC00346	Q8IVM7
Coiled-coil domain-containing protein 50	Q8IVM0	[Function: Involved in EGFR signaling.]
3-mercaptopyruvate sulfurtransferase	P25325	[Function: Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT), contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain, retina and vascular endothelial cells. Hydrogen sulfide H(2)S is an important synaptic modulator, signaling molecule, smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions.]