Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Rho GTPase-activating protein 36	B1AUC7	[Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.]
Elastin	P15502	[Function: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).]
Prostatic spermine-binding protein	P15501	[Function: This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding.]
Protein PBDC1	Q9BVG4
E3 ubiquitin-protein ligase TRIM62	Q9BVG3	[Function: E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.]
Gliadoralin-A	D3Z9M3	[Function: May play a role in the formation of the protective mucosal protein pellicle involved in the reinforcement and protection of oral mucosal epithelial surface.]
Kinesin-like protein KIFC3	Q9BVG8	[Function: Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance.]
Phosphatidylserine synthase 2	Q9BVG9	[Function: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine.]
Arrestin domain-containing protein 4	A0A0B4J1F4	[Function: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:27462458). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (By similarity). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). May play a role in glucose uptake (By similarity).]
Adenylyl cyclase-associated protein 2	P52481	[Function: May have a regulatory bifunctional role.]
Pyruvate kinase PKM	P52480	[Function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (PubMed:29996098).]
Ubiquitin-conjugating enzyme E2 E3	P52483	[Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination (By similarity). Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.]
Ubiquitin-conjugating enzyme E2 E1	P52482	[Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.]
Low affinity immunoglobulin gamma Fc region receptor IV	A0A0B4J1G0	[Function: Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059).]
Sterile alpha motif domain-containing protein 12	Q0VE29
Fez family zinc finger protein 1	Q0VDQ9	[Function: Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	Q9BVH7	[Function: Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins (By similarity).]
Peroxisome biogenesis factor 10	B1AUE5	[Function: Somewhat implicated in the biogenesis of peroxisomes.]
Dynein intermediate chain 2, axonemal	A2AC93	[Function: Part of the dynein complex of respiratory cilia.]
Zinc finger protein 367	Q0VDT2	[Function: Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes (By similarity).]