Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Protein C-ets-2	P15037	[Function: Transcription factor activating transcription. Binds specifically the GGA DNA motif in gene promoters and stimulates transcription of those genes (By similarity).]
Signaling threshold-regulating transmembrane adapter 1	Q9Y3P8	[Function: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.]
Testis-specific Y-encoded protein 1	Q01534	[Function: May be involved in sperm differentiation and proliferation.]
Protein FAM71F1	Q68FV5
LEM domain-containing protein 1	Q68G75
Zinc finger protein 610	Q8N9Z0	[Function: May be involved in transcriptional regulation.]
LIM/homeobox protein Lhx8	Q68G74	[Function: Transcription factor involved in differentiation of certain neurons and mesenchymal cells.]
Uncharacterized protein SPEM2	Q68FV4
Myelin transcription factor 1	Q01538	[Function: Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.]
Alpha-(1,3)-fucosyltransferase 11	Q68FV3	[Function: Probable fucosyltransferase.]
Rho GTPase-activating protein 9	Q9BRR9	[Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.]
Coiled-coil domain-containing protein 71L	Q8N9Z2
ADP-ribosylation factor-like protein 6-interacting protein 6	Q68FV2
Amyloid-beta A4 precursor protein-binding family B member 3	O95704	[Function: May modulate the internalization of amyloid-beta precursor protein.]
WASH complex subunit 4	Q3UMB9	[Function: Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875).]
Ubiquitin domain-containing protein 1	Q68FV8	[Function: May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2.]
Ribonuclease P protein subunit p29	O95707	[Function: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.]
Glycosylated lysosomal membrane protein	Q68FV6
E3 ubiquitin-protein ligase MARCH11	A6P320	[Function: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.]
Erythropoietin	P29676	[Function: Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.]