Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Tyrosine-protein kinase receptor UFO	P30530	[Function: (Microbial infection) Acts as a receptor for Ebolavirus, possibly through GAS6 binding to phosphatidyl-serine at the surface of virion envelope.]
Cyclic nucleotide-gated olfactory channel	Q62398	[Function: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.]
Sodium- and chloride-dependent GABA transporter 1	P30531	[Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.]
WAP four-disulfide core domain protein 6	Q9BQY6
Copine-7	H1UBN0	[Function: Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.]
Thyroid hormone receptor-associated protein 3	Q9Y2W1	[Function: Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes (PubMed:24043798).]
Death-inducer obliterator 1	Q8C9B9	[Function: Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed.]
WW domain-binding protein 11	Q9Y2W2	[Function: Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.]
Putative RNA-binding protein Luc7-like 2	Q9Y383	[Function: May bind to RNA via its Arg/Ser-rich domain.]
Proton-associated sugar transporter A	Q9Y2W3	[Function: Proton-associated glucose transporter in the brain.]
Nuclear envelope phosphatase-regulatory subunit 1	Q8N9A8	[Function: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.]
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11	Q6GQW0
Solute carrier organic anion transporter family member 2B1	Q8BXB6	[Function: Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.]
Multiple epidermal growth factor-like domains protein 11	A6BM72	[Function: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).]
ATPase family AAA domain-containing protein 2	Q6PL18	[Function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.]
Adenosine receptor A2a	P30543	[Function: Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:23994616).]
Alpha-2B adrenergic receptor	P30545	[Function: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.]
Erythroid differentiation-related factor 1	Q6GQV7	[Function: Transcription factor involved in erythroid differentiation. Involved in transcriptional activation of the globin gene (By similarity).]
Cytochrome c oxidase subunit 1	P05503	[Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.]
Substance-P receptor	P30548	[Function: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin K.]