Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Translation machinery-associated protein 7	Q9Y2S6
Solute carrier family 25 member 53	Q5H9E4
Vascular cell adhesion protein 1	P29533	[Function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.]
Polymerase delta-interacting protein 2	Q9Y2S7
Plasmolipin	Q9Y342	[Function: Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity).]
Lambda-crystallin homolog	Q9Y2S2
Mitochondrial 2-oxodicarboxylate carrier	Q9BQT8	[Function: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.]
Sorting nexin-24	Q9Y343	[Function: May be involved in several stages of intracellular trafficking.]
Calsyntenin-3	Q9BQT9	[Function: May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation.]
Cyclic AMP-dependent transcription factor ATF-7	P17544	[Function: Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.]
Proto-oncogene Wnt-3	P17553	[Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PubMed:10431240). Required for normal formation of the apical ectodermal ridge and for normal embryonic limb development (PubMed:12569130).]
Fibrinogen-like protein 1	Q71KU9	[Function: Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). Secreted by, and promotes growth of, hepatocytes (By similarity).]
ARL14 effector protein-like	Q3UKZ7
Axin-2	Q9Y2T1	[Function: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.]
Plasminogen activator inhibitor 2 type A	P29524	[Function: Inhibits urokinase-type plasminogen activator.]
von Willebrand factor A domain-containing protein 7	Q9Y334
Probable ATP-dependent RNA helicase DDX52	Q9Y2R4
CCAAT/enhancer-binding protein alpha	P05554	[Function: Directly and specifically enhances ribosomal DNA transcription interacting with RNA polymerase I-specific cofactors and inducing histone acetylation.]
28S ribosomal protein S17, mitochondrial	Q9Y2R5
Integrin alpha-M	P05555	[Function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (By similarity). It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (By similarity). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (PubMed:18685038).]