Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Fibroblast growth factor-binding protein 1	Q9QY10	[Function: Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth (By similarity).]
Ammonium transporter Rh type C	Q9QXP0	[Function: Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.]
Chorion-specific transcription factor GCMb	O09102	[Function: Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development.]
Protein SSUH2 homolog	Q8C3L1	[Function: Plays a role in odontogenesis.]
Neurogenic differentiation factor 4	O09105	[Function: Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina.]
Zinc finger X-chromosomal protein	P17012	[Function: Probable transcriptional activator.]
Ras GTPase-activating protein 4	Q6PFQ7	[Function: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14.]
ATP-dependent RNA helicase DDX25	Q9QY15	[Function: ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development.]
Zinc finger X-chromosomal protein	P17010	[Function: Probable transcriptional activator.]
Protein downstream neighbor of Son	Q9QXP4	[Function: Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability.]
Forkhead box protein E3	Q9QY14	[Function: Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:10652278, PubMed:10890982). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (PubMed:16199865). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (PubMed:10652278). Is required for morphogenesis and differentiation of the anterior segment of the eye (PubMed:17064680). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (By similarity).]
Phosphatidylinositol-glycan biosynthesis class F protein	O09101	[Function: Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI.]
Complement C1q tumor necrosis factor-related protein 1	Q9QXP7
Protein kinase C and casein kinase substrate in neurons 2 protein	Q9QY17	[Function: Regulates the morphogenesis and endocytosis of caveolae (PubMed:22718246). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.]
ATP-dependent RNA helicase DDX25	Q9QY16	[Function: ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity).]
Endothelial transcription factor GATA-2	O09100	[Function: Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.]
E3 ubiquitin-protein ligase makorin-1	Q9QXP6	[Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase (By similarity). Has negative and positive effects on RNA polymerase II-dependent transcription.]
Protein phosphatase 1A	P20650	[Function: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling (By similarity). Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity).]
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	P20651	[Function: Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32.]
Interferon alpha-16	P05015	[Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.]