Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Annexin-2 receptor	Q3ZCQ2	[Function: May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.]
Membrane protein FAM174B	Q3ZCQ3	[Function: Essential for Golgi structural integrity.]
INO80 complex subunit E	Q8NBZ0	[Function: Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.]
Uridine 5'-monophosphate synthase	P13439
Trophoblast-specific protein alpha	P13438	[Function: It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy.]
UDP-glucuronic acid decarboxylase 1	Q8NBZ7	[Function: Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.]
Putative uncharacterized protein NEXN-AS1	Q8NBZ9
3-ketoacyl-CoA thiolase, mitochondrial	P13437	[Function: In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (Probable). Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies (Probable). Also displays hydrolase activity on various fatty acyl-CoAs (PubMed:16476568). Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (Probable). Abolishes BNIP3-mediated apoptosis and mitochondrial damage (By similarity).]
SMR1 protein	P13432	[Function: Sialorphin is an endogenous inhibitor of neprilysin. Inhibits the breakdown of Met-enkephalin and substance P in isolated tissue from the dorsal zone of the rat spinal cord. Has an analgesic effect when administered to rats by intravenous injection.]
C-type lectin domain family 10 member A	Q8IUN9	[Function: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.]
Hydroxyacyl-thioester dehydratase type 2, mitochondrial	P86397	[Function: Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.]
Zinc transporter ZIP4	Q78IQ7	[Function: Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.]
5'-3' exonuclease PLD3	Q8IV08	[Function: 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30312375). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation (PubMed:22428023). Plays a role in lysosomal homeostasis (PubMed:28128235). Involved in the regulation of endosomal protein sorting (PubMed:29368044).]
Carabin	Q8IV04	[Function: Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.]
Leucine rich adaptor protein 1-like	Q8IV03
Alanine aminotransferase 1	P25409	[Function: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).]
Synaptotagmin-12	Q8IV01	[Function: Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids (By similarity). Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity).]
Kinase suppressor of Ras 2	Q3UVC0	[Function: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Acts as MAP2K1/MEK1-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1. Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.]
Troponin I, slow skeletal muscle	P13413	[Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.]
Troponin I, fast skeletal muscle	P13412	[Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.]