Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Cytochrome c oxidase subunit 7B2, mitochondrial	Q8TF08	[Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.]
Dynein light chain roadblock-type 2	Q8TF09	[Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.]
Regucalcin	Q15493	[Function: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).]
Cytochrome P450 2C39	P56656	[Function: Metabolizes arachidonic acid to produce 14,15-cis-epoxyeicosatrienoic acid (EET).]
Protein transport protein Sec23A	Q15436	[Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane (By similarity).]
Cytochrome P450 2C38	P56655	[Function: Metabolizes arachidonic acid to produce 11,12-epoxyeicosatrienoic acid (EET).]
Protein phosphatase 1 regulatory subunit 7	Q15435	[Function: Regulatory subunit of protein phosphatase 1.]
Cytochrome P450 2C37	P56654	[Function: Metabolizes arachidonic acid to produce 12-hydroxyeicosatetraenoic acid (HETE).]
RNA-binding motif, single-stranded-interacting protein 2	Q15434
Cytohesin-1	Q15438	[Function: Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.]
Protein transport protein Sec23B	Q15437	[Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.]
Phosphofurin acidic cluster sorting protein 1	Q6VY07	[Function: Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.]
Gem-associated protein 5	Q8TEQ6	[Function: Required for the assembly of the SMN complex that plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:16857593, PubMed:18984161, PubMed:20513430). Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (PubMed:18984161). Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus (PubMed:18984161). GEMIN5 acts as the snRNA-binding protein of the SMN complex (PubMed:11714716, PubMed:16857593, PubMed:19377484, PubMed:19750007, PubMed:20513430, PubMed:27834343, PubMed:27881600, PubMed:27881601). Binds to the 7-methylguanosine cap of RNA molecules (PubMed:19750007, PubMed:27834343, PubMed:27881600, PubMed:27881601, Ref.25). Binds to the 3'-UTR of SMN1 mRNA and regulates its translation; does not affect mRNA stability (PubMed:25911097). May play a role in the regulation of protein synthesis via its interaction with ribosomes (PubMed:27507887).]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11	Q8TF27	[Function: Putative GTPase-activating protein.]
Zinc finger protein 721	Q8TF20	[Function: May be involved in transcriptional regulation.]
Sorting nexin-29	Q8TEQ0
Ankyrin repeat domain-containing protein 24	Q8TF21
Cytochrome P450 2C40	P56657	[Function: Metabolizes arachidonic acid to produce an unidentified metabolite that coelutes with 16-,17-, and 18-hydroxyeicosatetraenoic acid (HETE).]
SH3 domain and tetratricopeptide repeat-containing protein 2	Q8TF17
Centrosomal protein of 192 kDa	Q8TEP8	[Function: Required for mitotic centrosome maturation and bipolar spindle assembly (PubMed:25042804, PubMed:17980596, PubMed:18207742). Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication (PubMed:25042804, PubMed:17980596, PubMed:18207742). Centrosome-specific activating scaffold for AURKA and PLK1 (PubMed:25042804).]