Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
A disintegrin and metalloproteinase with thrombospondin motifs 17	Q8TE56
A disintegrin and metalloproteinase with thrombospondin motifs 16	Q8TE57
Leptin receptor overlapping transcript-like 1	Q6PDU4	[Function: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity).]
Mitochondrial cardiolipin hydrolase	Q8N2A8	[Function: Endonuclease that plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. piRNAs provide essential protection against the activity of mobile genetic elements (By similarity). piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation (By similarity). Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface (By similarity). Although it cannot be excluded that it can act as a phospholipase in some circumstances, it should be noted that cardiolipin hydrolase activity is either undetectable in vitro, or very low (PubMed:21397848). In addition, cardiolipin is almost exclusively found on the inner mitochondrial membrane, while PLD6 localizes to the outer mitochondrial membrane, facing the cytosol (PubMed:21397848). Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleaving either RNA or DNA substrates with similar affinity. Produces 5' phosphate and 3' hydroxyl termini, suggesting it could directly participate in the processing of primary piRNA transcripts (By similarity). Also acts as a regulator of mitochondrial shape through facilitating mitochondrial fusion (PubMed:17028579, PubMed:26711011).]
Nuclear transition protein 2	Q05952	[Function: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.]
UBX domain-containing protein 2A	P68543
ES1 protein homolog, mitochondrial	P56571
RB-associated KRAB zinc finger protein	Q8BQC8	[Function: May repress E2F-dependent transcription. May promote AR-dependent transcription.]
Contactin-associated protein like 5-1	Q0V8T6	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Contactin-associated protein like 5-3	Q0V8T7	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Contactin-associated protein like 5-2	Q0V8T8	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Contactin-associated protein like 5-1	Q0V8T9	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Nucleoside diphosphate kinase homolog 5	P56597	[Function: Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).]
Contactin-associated protein like 5-4	Q0V8T3	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Contactin-associated protein like 5-3	Q0V8T4	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
Contactin-associated protein like 5-2	Q0V8T5	[Function: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.]
A disintegrin and metalloproteinase with thrombospondin motifs 18	Q8TE60
Keratin-associated protein 5-3	Q6L8H2	[Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.]
Protein CXorf40A	Q8TE69	[Function: May have an important role of cell protection in inflammation reaction.]
Relaxin-3 receptor 2	Q8TDU9	[Function: High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.]