Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Polypyrimidine tract-binding protein 1	P17225	[Function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.]
Serine/threonine-protein kinase 40	Q7TNL4	[Function: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.]
CCAAT/enhancer-binding protein zeta	Q03701	[Function: Stimulates transcription from the HSP70 promoter.]
Dual specificity phosphatase 28	Q8BTR5	[Function: Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro). Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine. The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site.]
Voltage-dependent calcium channel subunit alpha-2/delta-2	Q6PHS9	[Function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G).]
Spermatogenesis-associated protein 16	Q8C636	[Function: Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.]
BTB/POZ domain-containing protein KCTD18	Q6PI47
Isoleucine--tRNA ligase, cytoplasmic	Q8BU30	[Function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.]
NTF2-related export protein 1	Q9QZV9	[Function: Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (By similarity).]
Aspartate--tRNA ligase, mitochondrial	Q6PI48
Ras-related protein Rap-2c	Q8BU31	[Function: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.]
Proline and serine-rich protein 2	Q8C5R2
Sorting nexin-13	Q6PHS6	[Function: May be involved in several stages of intracellular trafficking. Acts as a GAP for Galphas (By similarity). May play a role in endosome homeostasis.]
Acetolactate synthase-like protein	Q8BU33
Calcium-binding and spermatid-specific protein 1	Q8C633
Homeobox protein Nkx-6.3	Q3UHX8	[Function: Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.]
Putative methyltransferase C9orf114 homolog	Q3UHX9	[Function: Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level (By similarity).]
28 kDa heat- and acid-stable phosphoprotein	Q3UHX2
Protein FAM71E2	Q8N5Q1
Tripartite motif-containing protein 46	Q7TNM2	[Function: Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon formation, the establishment of neuronal polarity and proper neuronal migration.]