Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Golgi SNAP receptor complex member 1	O95249	[Function: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.]
Dynactin subunit 5	Q9QZB9
RING finger protein 44	Q3UHJ8
Spectrin beta chain, non-erythrocytic 1	Q01082	[Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.]
Splicing factor U2AF 35 kDa subunit	Q01081	[Function: Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.]
Methyl-CpG-binding domain protein 4	O95243	[Function: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.]
Protein TCL1B5	P56845
Integrin beta-4	Q64632	[Function: Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.]
Protein TCL1B4	P56844
Nucleolysin TIAR	Q01085	[Function: RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.]
Protein GREB1	Q3UHK3	[Function: May play a role in estrogen-stimulated cell proliferation.]
Proton myo-inositol cotransporter	Q3UHK1	[Function: H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.]
Protein MTSS 2	Q765P7	[Function: Involved in plasma membrane dynamics. Potentiated PDGF-mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation (PubMed:14752106). May function in actin bundling (PubMed:14752106).]
Urinary protein 2	P81828
Plasminogen receptor (KT)	D4ACN8	[Function: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9 (By similarity).]
Urinary protein 1	P81827
Protein PERCC1	A0A286YDK6	[Function: Plays a critical role in intestinal function by promoting the development of enteroendocrine cells (EECs) of the gastrointestinal tract and pancreas (PubMed:31217582). It is thereby required for normal enteroendocrine peptide hormone secretion (PubMed:31217582).]
Dual specificity protein phosphatase 1	Q64623	[Function: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.]
Potassium channel subfamily K member 5	O95279	[Function: pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.]
Cathepsin Q	Q9QZE3