Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Protein arginine methyltransferase NDUFAF7, mitochondrial	Q7L592	[Function: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:20406883, PubMed:24089531, PubMed:24838397). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex (PubMed:24089531).]
Stromal membrane-associated protein 2	Q7TN29	[Function: GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network.]
Endothelial cell-specific molecule 1	Q9QYY7	[Function: Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions (By similarity).]
Histone H2A type 1-F	Q64598	[Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.]
All-trans-retinol dehydrogenase [NAD(+)] ADH4	Q9QYY9	[Function: Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol (By similarity). Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate (PubMed:16081420). Also catalyzes the reduction of benzoquinones (By similarity).]
Putative phosphatidylinositol 4-kinase alpha-like protein P2	A4QPH2
Spastin	Q9QYY8	[Function: Involved in lipid metabolism by regulating the size and distribution of lipid droplets.]
Uncharacterized protein C16orf90 homolog	Q8BT88
Cardiac-enriched FHL2-interacting protein	D3Z1D3	[Function: Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.]
Membrane magnesium transporter 1	Q8N4V1	[Function: Mediates Mg(2+) transport.]
Lysosomal Pro-X carboxypeptidase	Q7TMR0	[Function: Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity).]
Zinc finger protein ZIC 2	O95409	[Function: Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.]
Neuritin-like protein	Q8C4W3
Angiogenic factor with G patch and FHA domains 1	Q7TN31	[Function: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion (By similarity).]
Protein cornichon homolog 1	O95406	[Function: Involved in the selective transport and maturation of TGF-alpha family proteins.]
Oxidation resistance protein 1	Q8N573	[Function: May be involved in protection from oxidative damage.]
Tumor necrosis factor receptor superfamily member 6B	O95407	[Function: Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.]
Synaptic vesicle 2-related protein	Q8N4V2
Proline-rich protein 5-like	A1L1K1	[Function: Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton. Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration. Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress. Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress.]
Anaphase-promoting complex subunit 5	A1L1K3	[Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).]