Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| Protein phosphatase 1L | Q5SGD2 | [Function: Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.] |
| Neuropeptide B | Q8NG41 | [Function: May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway.] |
| Serine palmitoyltransferase small subunit B | Q8NFR3 | [Function: Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction.] |
| Beta-defensin 105 | Q8NG35 | [Function: Has antibacterial activity.] |
| Zinc finger protein 69 homolog | Q49AA0 | [Function: Putative transcription factor that appears to regulate lipid metabolism.] |
| Coiled-coil domain-containing protein 148 | Q8NFR7 | |
| Interleukin-17 receptor E | Q8NFR9 | [Function: Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.] |
| Cellular nucleic acid-binding protein | P62633 | [Function: Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.] |
| ATP-sensitive inward rectifier potassium channel 10 | P49655 | [Function: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (By similarity).] |
| Beta-1,3-galactosyltransferase 4 | O88178 | [Function: Involved in GM1/GD1B/GA1 ganglioside biosynthesis.] |
| Elongation factor 1-alpha 2 | P62632 | [Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.] |
| Elongation factor 1-alpha 2 | P62631 | [Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.] |
| P2X purinoceptor 2 | P49653 | [Function: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity).] |
| Elongation factor 1-alpha 1 | P62630 | [Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.] |
| P2X purinoceptor 3 | P49654 | [Function: Receptor for ATP that acts as a ligand-gated cation channel (PubMed:7566120, PubMed:7566119). Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity).] |
| Structural maintenance of chromosomes protein 2 | Q8CG48 | [Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).] |
| Membrane cofactor protein | O88174 | [Function: May be involved in the fusion of the spermatozoa with the oocyte during fertilization.] |
| Peroxisome assembly protein 12 | O88177 | [Function: Required for protein import into peroxisomes.] |
| Cellular nucleic acid-binding protein | P62634 | [Function: Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.] |
| Testis-specific protein 10-interacting protein | Q66MI6 |