Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| von Ebner gland protein 1 | P20289 | [Function: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system.] |
| Magnesium transporter NIPA3 | Q8BMW7 | [Function: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+).] |
| Adhesion G protein-coupled receptor B3 | Q80ZF8 | [Function: Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (PubMed:23628982). Promotes myoblast fusion through ELMO/DOCK1 (By similarity).] |
| Synaptotagmin-like protein 1 | Q99N80 | [Function: Binds phosphatidylinositol 3,4,5-trisphosphate (By similarity). May play a role in vesicle trafficking. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes.] |
| Serine/threonine-protein kinase 31 | Q99MW1 | |
| Kelch domain-containing protein 10 | Q6PAR0 | [Function: Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5.] |
| Putative chondrosarcoma-associated gene 1 protein | Q6PB30 | |
| Transforming growth factor beta regulator 1 | Q3UB74 | [Function: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.] |
| Protein phosphatase 1 regulatory subunit 37 | O75864 | [Function: Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.] |
| Trafficking protein particle complex subunit 6A | O75865 | [Function: May play a role in vesicular transport during the biogenesis of melanosomes.] |
| Ras-related GTP-binding protein B | Q5VZM2 | [Function: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.] |
| 60S ribosomal protein L21 | P20280 | [Function: Component of the large ribosomal subunit.] |
| Retinol dehydrogenase 10 | Q80ZF7 | [Function: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal.] |
| 39S ribosomal protein L43, mitochondrial | Q99N89 | |
| Olfactory receptor 181 | Q8VGQ7 | [Function: Potential odorant receptor.] |
| GA-binding protein subunit beta-2 | Q8TAK5 | [Function: May function as transcription factor capable of interacting with purine rich repeats (GA repeats).] |
| 28S ribosomal protein S5, mitochondrial | Q99N87 | |
| 28S ribosomal protein S18b, mitochondrial | Q99N84 | |
| GTPase-activating protein and VPS9 domain-containing protein 1 | Q6PAR5 | [Function: Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. Acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside the cells. Upon insulin stimulation, it is translocated to the plasma membrane, releasing LC2A4/GLUT4 from intracellular storage vesicles. Also involved in EGFR trafficking and degradation, possibly by promoting EGFR ubiquitination and subsequent degradation by the proteasome. Has GEF activity for Rab5 and GAP activity for Ras.] |
| Gamma-tubulin complex component 3 | P58854 | [Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.] |