Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Eukaryotic translation initiation factor 4 gamma 3	Q80XI3	[Function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1 (By similarity).]
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Q80XI4	[Function: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.]
Glutathione S-transferase A2	P10648	[Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.]
Glutathione S-transferase Mu 1	P10649	[Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.]
Zinc finger protein 639	Q99KZ6	[Function: Binds DNA and may function as a transcriptional repressor.]
cAMP-dependent protein kinase type I-alpha regulatory subunit	P10644	[Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.]
Chromogranin-A	P10645	[Function: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.]
Tissue factor pathway inhibitor	P10646	[Function: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.]
Zinc finger protein 697	Q569E7	[Function: May be involved in transcriptional regulation.]
Protein XRP2	O75695	[Function: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.]
Complement component C7	P10643	[Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.]
Protein MENT	Q569E4	[Function: Involved in control of cellular proliferation. Onconcogenic modifier contributing to the tumor suppressor function of DNMT3B.]
Nuclear pore complex protein Nup155	O75694	[Function: Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.]
Small subunit processome component 20 homolog	O75691	[Function: Involved in 18S pre-rRNA processing. Associates with U3 snoRNA.]
Keratin-associated protein 5-8	O75690	[Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.]
Heterogeneous nuclear ribonucleoproteins A2/B1	P22626	[Function: (Microbial infection) Involved in the transport of HIV-1 genomic RNA out of the nucleus, to the microtubule organizing center (MTOC), and then from the MTOC to the cytoplasm: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) sequence motifs present on HIV-1 genomic RNA, and promotes its transport.]
Ubiquitin carboxyl-terminal hydrolase 17-like protein 22	D6RA61	[Function: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.]
Radiation-inducible immediate-early gene IEX-1	P46695	[Function: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.]
Radiation-inducible immediate-early gene IEX-1	P46694	[Function: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival (By similarity). As a member of the NUPR1/RELB/IER3 survival pathway, may allow the development of pancreatic intraepithelial neoplasias.]
Acetylcholine receptor subunit epsilon	P09660	[Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.]