Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
IQ domain-containing protein F2	Q8IXL9
Medium-wave-sensitive opsin 3	P0DN78	[Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.]
Heat shock 70 kDa protein 1A	P0DMV8	[Function: (Microbial infection) In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.]
Medium-wave-sensitive opsin 2	P0DN77	[Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.]
Methionine-R-sulfoxide reductase B3	Q8IXL7	[Function: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.]
Splicing factor U2AF 35 kDa subunit-like protein	P0DN76	[Function: Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.]
Extracellular serine/threonine protein kinase FAM20C	Q8IXL6	[Function: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).]
Periphilin-1	Q8NEY8	[Function: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). The HUSH complex is also involved in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (PubMed:12853457).]
C-type lectin domain family 12 member B	Q2HXU8	[Function: Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.]
Short-chain dehydrogenase/reductase family 9C member 7	Q8NEX9	[Function: Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.]
Zinc finger protein 397	Q8NF99	[Function: Isoform 3 acts as a DNA-dependent transcriptional repressor.]
39S ribosomal protein L41, mitochondrial	Q8IXM3	[Function: Component of the mitochondrial ribosome large subunit (PubMed:28892042, PubMed:25838379, PubMed:25278503). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).]
Chromatin complexes subunit BAP18	Q8IXM2	[Function: Component of chromatin complexes such as the MLL1/MLL and NURF complexes.]
Isthmin-1	B1AKI9	[Function: Acts as an angiogenesis inhibitor.]
Putative olfactory receptor 8G3 pseudogene	P0DMU2	[Function: Odorant receptor.]
NEDD8-conjugating enzyme UBE2F	Q969M7	[Function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.]
Mitochondrial import receptor subunit TOM40B	Q969M1	[Function: Potential channel-forming protein implicated in import of protein precursors into mitochondria.]
Gap junction alpha-10 protein	Q969M2	[Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning (By similarity).]
Protein YIPF5	Q969M3	[Function: Plays a role in transport between endoplasmic reticulum and Golgi.]
Vacuolar protein sorting-associated protein 37A	Q8NEZ2	[Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.]