Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| Oncoprotein-induced transcript 3 protein | Q8R4V5 | [Function: May be involved in hepatocellular function and development.] |
| GDP-Man_Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase | Q3TZM9 | [Function: Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain (By similarity).] |
| XK-related protein 9 | Q5GH70 | |
| Carboxypeptidase Z | Q8R4V4 | [Function: Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing (By similarity).] |
| Phosphoribosyl pyrophosphate synthase-associated protein 2 | Q8R574 | [Function: Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.] |
| Solute carrier family 35 member F1 | Q8BGK5 | [Function: Putative solute transporter.] |
| Cadherin-3 | P22223 | [Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.] |
| V-type proton ATPase subunit d 2 | Q80SY3 | [Function: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in coupling of proton transport and ATP hydrolysis. Regulator of osteoclast fusion and bone formation.] |
| E3 ubiquitin-protein ligase MIB1 | Q80SY4 | [Function: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation (By similarity). Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.] |
| Pre-mRNA-splicing factor 38B | Q80SY5 | [Function: May be required for pre-mRNA splicing.] |
| XK-related protein 7 | Q5GH56 | |
| Telomeric repeat-binding factor 2-interacting protein 1 | Q5EAN7 | [Function: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes (By similarity).] |
| Adenosine deaminase-like protein | Q80SY6 | [Function: Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A).] |
| XK-related protein 6 | Q5GH57 | |
| XK-related protein 4 | Q5GH59 | |
| Fibroblast growth factor 5 | P48807 | [Function: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity).] |
| PRAME family member 17 | Q5VTA0 | |
| Procollagen C-endopeptidase enhancer 2 | Q8R4W6 | [Function: Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.] |
| Probable protein phosphatase 1N | Q8BGL1 | |
| Cilia- and flagella-associated protein 99 | D6REC4 |