Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	P22061	[Function: Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.]
Sodium-dependent glucose transporter 1	Q80T22	[Function: May function as a sodium-dependent glucose transporter (PubMed:12590146). Potential channels for urea in the inner medulla of kidney (PubMed:26423860).]
MKRN2 opposite strand protein	H3BPM6
Synaptotagmin-like protein 5	Q80T23	[Function: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids (By similarity).]
Zinc finger protein GLI4	P10075
Zinc finger protein 26	P10076	[Function: May be involved in transcriptional regulation.]
Zinc finger protein 27	P10077	[Function: May be involved in transcriptional regulation.]
Protein CREG2	Q8BGC9
ADAMTS-like protein 4	Q80T21	[Function: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity).]
Zinc finger protein 28	P10078	[Function: May be involved in transcriptional regulation. May have a role in embryonic development.]
Peptide YY	P10082	[Function: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.]
Chymotrypsin-like elastase family member 3A	P09093	[Function: Efficient protease with alanine specificity but only little elastolytic activity.]
Solute carrier organic anion transporter family member 4C1	Q8BGD4	[Function: Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.]
Carnitine O-palmitoyltransferase 1, brain isoform	Q8BGD5	[Function: May play a role in lipid metabolic process.]
Sodium-coupled neutral amino acid transporter 9	Q8BGD6	[Function: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids. Acts as an arginine sensor. Following activation by arginine binding, mediates transport of leucine, tyrosine and phenylalanine with high efficiency, and is required for the efficient utilization of these amino acids after lysosomal protein degradation.]
Homeobox protein Hox-A6	P09092	[Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.]
Myoblast determination protein 1	P10085	[Function: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:16901893). Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (PubMed:21798092, PubMed:3175662).]
Paraneoplastic antigen Ma6E	A0A0J9YXQ4
Uncharacterized protein C3orf14 homolog	Q8BGD0
Mitofusin-2	Q8R500	[Function: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:14561718, PubMed:15322553, PubMed:12589796, PubMed:12598526). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (PubMed:12598526). Plays an important role in the regulation of vascular smooth muscle cell proliferation (PubMed:15322553). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria (By similarity). Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity). Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (By similarity).]