Terminology Service for NFDI4Health
All terms in BAO
| Label | Id | Description |
|---|---|---|
| EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor | CHEBI_65065 | |
| DNA aptamer | BAO_0000495 | [Aptamers are synthetic affinity probes. DNA aptamers are oligonucleotides that bind to a specific target molecule, such as small molecules, proteins, nucleic acids and cells. They are created by selecting them from a large random sequence pool through repeated rounds of in vitro selection.] |
| chloramphenicol acetyltransferase induction | BAO_0000494 | [Chloramphenicol acetyltransferase (CAT) gene is attached to the regulatory sequence of a gene of interest. When induced to express, CAT breaks down the antibiotic chloramphenicol resulting in a resistance against that antibiotic. The effect of a perturbagen on the expression of the gene of interest could easily be monitored by the gain of antibiotic resistance by the cells.] |
| analytical array | BAO_0000492 | [In this method, antibodies or peptides are spotted on a support to be hybridized to analytes in complex mixtures of proteins.] |
| protein array | BAO_0000505 | [This includes spotting purified proteins, cell or tissue lysates, antibodies, or peptides in order to quantify the proteome, or study protein-protein, protein-DNA, protein-small molecule interactions and enzyme activity. ] |
| time dependent inhibition | BAO_0000491 | [Time-dependent inhibitors bind slowly to the enzyme on the time scale of enzymatic turnover, and thus display a change in initial velocity with time. This has the effect of slowing the observed onset of inhibition.] |
| biliary tract neoplasm | DOID_0050625 | [A hepatobiliary benign neoplasm located_in the biliary tract.] |
| EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor | CHEBI_65064 | |
| cell movement measurement method | BAO_0000499 | [The technologies used to measure the movement of cells and organelles (phenotype). These are detected by microscopy.] |
| metachromatic leukodystrophy | DOID_10581 | [A sphingolipidosis characterized by the accumulation of sulfatides in cells, especially the myelin producing cells of the nervous system.] |
| hyperuricemia | DOID_1920 | [An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood.] |
| Refsum disease | DOID_10582 | |
| familial atrial fibrillation | DOID_0050650 | [An atrial fibrillation that has_material_basis_in autosomal dominant inheritance of the familial atrial fibrillation (ATFB) genes.] |
| atrial fibrillation | DOID_0060224 | [A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.] |
| atrioventricular septal defect | DOID_0050651 | [A congenital heart septal defect characterized by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum, thus allowing extra blood to circulate the lungs.] |
| Krabbe disease | DOID_10587 | |
| adrenoleukodystrophy | DOID_10588 | [A leukodystrophy that disrupts the breakdown of very-long-chain fatty acids resulting in progressive brain damage, failure of the adrenal glands and eventually death.] |
| retinitis pigmentosa | DOID_10584 | [A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.] |
| EC 3.1.3.11 (fructose-bisphosphatase) inhibitor | CHEBI_65056 | |
| unpurified | BAO_0000465 | [Crude protein preparation] |